Experiment description of studies that identified Hnrnpm in sEVs

1 Experiment ID 907 MISEV standards ✔ EM Biophysical techniques ✔ Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a Enriched markers ✔ HSPA5 Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 37309723     Organism Mus musculus Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S." Journal name Proteomics Publication year 2023 Sample Colon cancer cells Sample name C26 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 1117 MISEV standards ✘ Biophysical techniques ✔ Cd81|Icam1 Enriched markers ✘ Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 34957415     Organism Mus musculus Experiment description Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Authors "García-Silva S, Benito-Martín A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÁ, Torres-Ruiz R, Rodríguez-Perales S, Martínez L, Pérez-Martínez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, Martínez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, Megías D, Mehrara BJ, Lyden D, Peinado H." Journal name Nat Cancer Publication year 2021 Sample Melanoma cells Sample name B16-F1R2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

3 Experiment ID 1118 MISEV standards ✘ Biophysical techniques ✔ Cd81|Icam1 Enriched markers ✘ Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 34957415     Organism Mus musculus Experiment description Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Authors "García-Silva S, Benito-Martín A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÁ, Torres-Ruiz R, Rodríguez-Perales S, Martínez L, Pérez-Martínez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, Martínez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, Megías D, Mehrara BJ, Lyden D, Peinado H." Journal name Nat Cancer Publication year 2021 Sample Melanoma cells Sample name B16-F1R2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

4 Experiment ID 188 MISEV standards ✔ EM Biophysical techniques ✔ GAPDH|UCHL1|HSP90 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 19351151     Organism Mus musculus Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells. Authors "Lee HS, Jeong J, Lee KJ." Journal name J Proteome Res Publication year 2009 Sample Pancreatic cells Sample name Pancreatic beta cell (NIT-1) Isolation/purification methods Differential centrifugation Sucrose density gradient Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

5 Experiment ID 908 MISEV standards ✔ EM Biophysical techniques ✔ Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a Enriched markers ✔ HSPA5 Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 37309723     Organism Mus musculus Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S." Journal name Proteomics Publication year 2023 Sample T-cell lymphoma cells Sample name EL4 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for Hnrnpm

Protein Interactor ExoCarta ID Identification method PubMed Species 1 Sf3a3 75062 Co-fractionation Mus musculus 2 Ddx5 13207 Co-fractionation Mus musculus 3 Kctd13   Affinity Capture-MS Mus musculus 4 Fxr1 14359 Affinity Capture-MS Mus musculus 5 Ubc   Reconstituted Complex Mus musculus 6 Abcf1 224742 Co-fractionation Mus musculus 7 Prpf4b 19134 Co-fractionation Mus musculus 8 Prpf8 192159 Co-fractionation Mus musculus 9 Mettl21e   Affinity Capture-MS Mus musculus 10 Cdc5l 71702 Co-fractionation Mus musculus 11 Gpatch1   Co-fractionation Mus musculus 12 Rbmx   Co-fractionation Mus musculus 13 Bcas2   Co-fractionation Mus musculus 14 Cebpa   Affinity Capture-MS Mus musculus 15 Tada2a   Co-fractionation Mus musculus 16 Tfe3   Affinity Capture-MS Mus musculus 17 Snrnp200 320632 Co-fractionation Mus musculus 18 Iqcb1   Affinity Capture-MS Mus musculus 19 Mecp2   Affinity Capture-MS Mus musculus 20 Pnn   Co-fractionation Mus musculus 21 Cwc15   Co-fractionation Mus musculus 22 Tmem173   Proximity Label-MS Mus musculus 23 Fzr1   Affinity Capture-MS Mus musculus 24 Tfip11   Co-fractionation Mus musculus 25 Dmrt2   Affinity Capture-MS Mus musculus Reconstituted Complex Mus musculus Affinity Capture-Western Mus musculus 26 Nanog   Affinity Capture-MS Mus musculus 27 Ppwd1   Co-fractionation Mus musculus 28 Invs   Affinity Capture-MS Mus musculus 29 Slu7   Co-fractionation Mus musculus 30 Ddx41   Co-fractionation Mus musculus 31 Eed   Affinity Capture-MS Mus musculus 32 Myef2 17876 Co-fractionation Mus musculus 33 Snrnp70 20637 Co-fractionation Mus musculus 34 Dgcr8   Co-fractionation Mus musculus 35 Ttll11   Co-fractionation Mus musculus 36 Fancd2   Affinity Capture-MS Mus musculus View the network

Pathways in which Hnrnpm is involved

No pathways found