Gene description for AHRR
Gene name aryl-hydrocarbon receptor repressor
Gene symbol AHRR
Other names/aliases AHH
AHHR
bHLHe77
Species Homo sapiens
 Database cross references - AHRR
ExoCarta ExoCarta_57491
Entrez Gene 57491
HGNC 346
MIM 606517
UniProt A9YTQ3  
 AHRR identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for AHRR
Molecular Function
    DNA binding GO:0003677 IEA
    protein dimerization activity GO:0046983 IEA
    signal transducer activity GO:0004871 IEA
    RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription GO:0001191 IBA
Biological Process
    positive regulation of transcription from RNA polymerase II promoter GO:0045944 IBA
    negative regulation of transcription from RNA polymerase II promoter GO:0000122 IBA
    signal transduction GO:0007165 IEA
    response to xenobiotic stimulus GO:0009410 IBA
    positive regulation of protein sumoylation GO:0033235 IEA
    transcription, DNA-templated GO:0006351 IEA
Subcellular Localization
    nuclear aryl hydrocarbon receptor complex GO:0034753 IBA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified AHRR in exosomes
1
Experiment ID 126
ISEV standards
✘ EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for AHRR
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which AHRR is involved
No pathways found





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