Gene description for AHRR
Gene name aryl-hydrocarbon receptor repressor
Gene symbol AHRR
Other names/aliases AHH
AHHR
bHLHe77
Species Homo sapiens
 Database cross references - AHRR
ExoCarta ExoCarta_57491
Vesiclepedia VP_57491
Entrez Gene 57491
HGNC 346
MIM 606517
UniProt A9YTQ3  
 AHRR identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for AHRR
Molecular Function
    transcription cis-regulatory region binding GO:0000976 IBA
    DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 ISA
    nuclear receptor activity GO:0004879 IBA
    protein binding GO:0005515 IPI
    protein dimerization activity GO:0046983 IEA
Biological Process
    regulation of transcription by RNA polymerase II GO:0006357 IBA
    regulation of transcription by RNA polymerase II GO:0006357 IEA
    xenobiotic metabolic process GO:0006805 IEA
    intracellular receptor signaling pathway GO:0030522 IEA
Subcellular Localization
    chromatin GO:0000785 ISA
    nucleus GO:0005634 IBA
    nucleoplasm GO:0005654 TAS
    cytoplasm GO:0005737 IEA
    aryl hydrocarbon receptor complex GO:0034751 IBA
 Experiment description of studies that identified AHRR in sEVs
1
Experiment ID 126
MISEV standards
Biophysical techniques
GAPDH
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for AHRR
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HDAC4  
Affinity Capture-Western Homo sapiens
2 ANKRA2  
Affinity Capture-Western Homo sapiens
3 ESR1  
Affinity Capture-Western Homo sapiens
4 ARNT 405
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
5 HDAC5 10014
Affinity Capture-Western Homo sapiens
View the network image/svg+xml



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