Gene description for LY9
Gene name lymphocyte antigen 9
Gene symbol LY9
Other names/aliases CD229
SLAMF3
hly9
mLY9
Species Homo sapiens
 Database cross references - LY9
ExoCarta ExoCarta_4063
Vesiclepedia VP_4063
Entrez Gene 4063
HGNC 6730
MIM 600684
UniProt Q9HBG7  
 LY9 identified in exosomes derived from the following tissue/cell type
Urine 21595033    
Urine 21595033    
Urine 21595033    
 Gene ontology annotations for LY9
Biological Process
    immune response GO:0006955 IBA
    cell adhesion GO:0007155 IEA
    positive regulation of interleukin-17 production GO:0032740 IDA
    T cell activation GO:0042110 IBA
    innate immune response GO:0045087 IEA
    T-helper 17 cell lineage commitment GO:0072540 IDA
Subcellular Localization
    plasma membrane GO:0005886 IDA
    external side of plasma membrane GO:0009897 IBA
 Experiment description of studies that identified LY9 in exosomes
1
Experiment ID 193
MISEV standards
EM
Biophysical techniques
CD63|CD9
Enriched markers
PHB
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 194
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 195
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for LY9
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DDX19B 11269
Affinity Capture-MS Homo sapiens
2 IDUA 3425
Affinity Capture-MS Homo sapiens
3 AP2M1 1173
Two-hybrid Homo sapiens
4 EDEM3 80267
Affinity Capture-MS Homo sapiens
5 PTPN11 5781
Affinity Capture-Western Homo sapiens
6 SH2D1A 4068
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
7 HLA-F 3134
Affinity Capture-MS Homo sapiens
8 Sh2d1b1  
Two-hybrid Mus musculus
Affinity Capture-Western Mus musculus
9 GUSB 2990
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which LY9 is involved
No pathways found





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