Gene description for ANG
Gene name	angiogenin, ribonuclease, RNase A family, 5
Gene symbol	ANG
Other names/aliases	ALS9 HEL168 RAA1 RNASE4 RNASE5
Species	Homo sapiens
Database cross references - ANG
ExoCarta	ExoCarta_283
Vesiclepedia	VP_283
Entrez Gene	283
HGNC	483
MIM	105850
UniProt	P03950
ANG identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for ANG

Molecular Function     DNA binding GO:0003677 IC     actin binding GO:0003779 IDA     endonuclease activity GO:0004519 TAS     RNA endonuclease activity GO:0004521 TAS     RNA nuclease activity GO:0004540 IBA     RNA nuclease activity GO:0004540 IDA     tRNA-specific ribonuclease activity GO:0004549 IDA     signaling receptor binding GO:0005102 IDA     copper ion binding GO:0005507 IDA     protein binding GO:0005515 IPI     heparin binding GO:0008201 IDA     rRNA binding GO:0019843 TAS     peptide binding GO:0042277 IDA     protein homodimerization activity GO:0042803 IDA     ribosome binding GO:0043022 IDA     receptor ligand activity GO:0048018 IDA Biological Process     angiogenesis GO:0001525 IBA     angiogenesis GO:0001525 IDA     angiogenesis GO:0001525 IDA     angiogenesis GO:0001525 IMP     angiogenesis GO:0001525 TAS     ovarian follicle development GO:0001541 NAS     oocyte maturation GO:0001556 NAS     response to hypoxia GO:0001666 IDA     response to hypoxia GO:0001666 NAS     response to yeast GO:0001878 IDA     placenta development GO:0001890 NAS     positive regulation of endothelial cell proliferation GO:0001938 IDA     cell communication GO:0007154 NAS     signal transduction GO:0007165 IDA     rRNA transcription GO:0009303 IDA     rRNA transcription GO:0009303 IMP     response to hormone GO:0009725 IDA     tRNA decay GO:0016078 TAS     cell migration GO:0016477 IMP     antibacterial humoral response GO:0019731 IBA     antibacterial humoral response GO:0019731 IDA     antifungal humoral response GO:0019732 IDA     signaling GO:0023052 IDA     actin filament polymerization GO:0030041 ISS     negative regulation of translation in response to stress GO:0032055 IDA     stress granule assembly GO:0034063 IDA     positive regulation of phosphorylation GO:0042327 IDA     homeostatic process GO:0042592 NAS     negative regulation of apoptotic process GO:0043066 ISS     innate immune response GO:0045087 IBA     innate immune response GO:0045087 IDA     negative regulation of smooth muscle cell proliferation GO:0048662 IDA     positive regulation of protein secretion GO:0050714 IDA     positive regulation of protein secretion GO:0050714 ISS     defense response to Gram-positive bacterium GO:0050830 IBA     defense response to Gram-positive bacterium GO:0050830 IDA     antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 IBA     antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 IDA     hematopoietic stem cell proliferation GO:0071425 IDA Subcellular Localization     extracellular region GO:0005576 TAS     basement membrane GO:0005604 IDA     extracellular space GO:0005615 IBA     extracellular space GO:0005615 IDA     nucleus GO:0005634 IDA     nucleus GO:0005634 IDA     chromosome GO:0005694 IDA     nucleolus GO:0005730 IDA     nucleolus GO:0005730 ISS     cytoplasm GO:0005737 IDA     cytosol GO:0005829 TAS     cytoplasmic stress granule GO:0010494 IDA     actin cytoskeleton GO:0015629 IDA     endocytic vesicle GO:0030139 IDA     growth cone GO:0030426 ISS     angiogenin-PRI complex GO:0032311 IDA     angiogenin-PRI complex GO:0032311 IPI     neuronal cell body GO:0043025 ISS