Experiment description of studies that identified TRIM58 in sEVs

1 Experiment ID 231 MISEV standards ✘ Biophysical techniques ✔ Alix|CD63|CD9 Enriched markers ✘ Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25332113     Organism Homo sapiens Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G." Journal name Transfusion Publication year 2015 Sample Platelets Sample name PL-Exs - Rep 1 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient Flotation density 1.12-1.15 g/mL Molecules identified in the study Protein Lipids Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 232 MISEV standards ✘ Biophysical techniques ✘ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25332113     Organism Homo sapiens Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G." Journal name Transfusion Publication year 2015 Sample Platelets Sample name PL-Exs - Rep 2 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient Flotation density 1.12-1.15 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

3 Experiment ID 233 MISEV standards ✘ Biophysical techniques ✘ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25332113     Organism Homo sapiens Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G." Journal name Transfusion Publication year 2015 Sample Platelets Sample name PL-Exs - Rep 3 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient Flotation density 1.12-1.15 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for TRIM58

Protein Interactor ExoCarta ID Identification method PubMed Species 1 TLR2 7097 Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 2 FBXW7   Synthetic Lethality Homo sapiens 3 DYNC1H1 1778 Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens 4 ACTB 60 Affinity Capture-MS Homo sapiens 5 HMGA1 3159 Affinity Capture-MS Homo sapiens 6 HNRNPU 3192 Affinity Capture-MS Homo sapiens 7 UBE2D3 7323 Reconstituted Complex Homo sapiens 8 TUBA1A 7846 Affinity Capture-MS Homo sapiens 9 DYNC1I1   Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Biochemical Activity Homo sapiens 10 MPRIP 23164 Affinity Capture-MS Homo sapiens 11 DDX3X 1654 Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens 12 TRIM58 25893 Biochemical Activity Homo sapiens Biochemical Activity Homo sapiens 13 KRT5 3852 Affinity Capture-MS Homo sapiens 14 DYNC2LI1 51626 Affinity Capture-MS Homo sapiens 15 TMOD3 29766 Affinity Capture-MS Homo sapiens 16 SRSF3 6428 Affinity Capture-MS Homo sapiens 17 DYNC1LI2 1783 Affinity Capture-MS Homo sapiens View the network

Pathways in which TRIM58 is involved

No pathways found