Gene description for ANKRD23
Gene name ankyrin repeat domain 23
Gene symbol ANKRD23
Other names/aliases DARP
MARP3
Species Homo sapiens
 Database cross references - ANKRD23
ExoCarta ExoCarta_200539
Entrez Gene 200539
HGNC 24470
MIM 610736
UniProt Q86SG2  
 ANKRD23 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for ANKRD23
Molecular Function
    titin binding GO:0031432 IPI
Biological Process
    response to mechanical stimulus GO:0009612 IEA
Subcellular Localization
    actin cytoskeleton GO:0015629 IDA
    nucleoplasm GO:0005654 IDA
    myofibril GO:0030016 IEA
    intercalated disc GO:0014704 IEA
    cytoplasm GO:0005737 IDA
 Experiment description of studies that identified ANKRD23 in exosomes
1
Experiment ID 224
ISEV standards
EM|AFM
EV Biophysical techniques
Alix|TSG101
EV Cytosolic markers
CD63|CD81
EV Membrane markers
GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for ANKRD23
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MYPN 84665
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
2 TTN 7273
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which ANKRD23 is involved
No pathways found





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