Experiment description of studies that identified RMDN2 in sEVs

1 Experiment ID 834 MISEV standards ✔ EM Biophysical techniques ✔ LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 835 MISEV standards ✔ EM Biophysical techniques ✔ CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

3 Experiment ID 191 MISEV standards ✘ Biophysical techniques ✔ Alix|CD81|CD9 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 20124223     Organism Homo sapiens Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK." Journal name Mol Cell Proteomics Publication year 2010 Sample Squamous carcinoma cells Sample name Squamous carcinoma cell (A431) Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for RMDN2

Protein Interactor ExoCarta ID Identification method PubMed Species 1 HSD17B11 51170 Two-hybrid Homo sapiens 2 RDH10 157506 Two-hybrid Homo sapiens 3 VAPB 9217 Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Two-hybrid Homo sapiens 4 VAPA 9218 Affinity Capture-MS Homo sapiens Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 5 RTN3 10313 Two-hybrid Homo sapiens 6 YWHAB 7529 Affinity Capture-MS Homo sapiens 7 SLC39A8 64116 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 8 TNFRSF10D 8793 Two-hybrid Homo sapiens 9 Rmdn3   Affinity Capture-MS Mus musculus 10 MTCH2 23788 Proximity Label-MS Homo sapiens 11 ARMC6 93436 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 12 OCIAD1 54940 Proximity Label-MS Homo sapiens 13 AGTRAP 57085 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 14 DIABLO 56616 Two-hybrid Homo sapiens 15 SAAL1 113174 Affinity Capture-MS Homo sapiens 16 THAP4 51078 Two-hybrid Homo sapiens 17 CMTM5   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 18 STX1A 6804 Two-hybrid Homo sapiens 19 NEUROG3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 20 AKAP1 8165 Proximity Label-MS Homo sapiens 21 ACBD5 91452 Proximity Label-MS Homo sapiens 22 RMDN3 55177 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 23 SLC25A46 91137 Proximity Label-MS Homo sapiens View the network

Pathways in which RMDN2 is involved

No pathways found