Gene description for CSN1S1 |
Gene name |
casein alpha s1 |
Gene symbol |
CSN1S1 |
Other names/aliases |
CASA CSN1 |
Species |
Homo sapiens |
Database cross references - CSN1S1 |
ExoCarta |
ExoCarta_1446 |
Entrez Gene |
1446 |
HGNC |
2445 |
MIM |
115450 |
UniProt |
P47710
|
CSN1S1 identified in exosomes derived from the following tissue/cell type |
Breast milk
|
17641064
|
Breast milk
|
17641064
|
Gene ontology annotations for CSN1S1 |
|
Experiment description of studies that identified CSN1S1 in exosomes |
1 |
Experiment ID |
46 |
ISEV standards |
✔
EM|IEM
|
EV Biophysical techniques |
✔
HSC70
|
EV Cytosolic markers |
✔
CD63|MHCII|CD81|CD86
|
EV Membrane markers |
✔
CANX
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
17641064
|
Organism |
Homo sapiens |
Experiment description |
Exosomes with immune modulatory features are present in human breast milk. |
Authors |
Admyre C, Johansson SM, Qazi KR, Filen JJ, Lahesmaa R, Norman M, Neve EP, Scheynius A, Gabrielsson S |
Journal name |
JIMMU
|
Publication year |
2007 |
Sample |
Breast milk |
Sample name |
Breast milk - Colostrum |
Isolation/purification methods |
Differential centrifugation Filtration Sucrose density gradient |
Flotation density |
1.10-1.18 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry [QSTAR] Western blotting Immunoelectron Microscopy FACS |
|
|
2 |
Experiment ID |
48 |
ISEV standards |
✔
EM|IEM
|
EV Biophysical techniques |
✔
HSC70
|
EV Cytosolic markers |
✔
CD63|CD86|MHCII
|
EV Membrane markers |
✔
CANX
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
17641064
|
Organism |
Homo sapiens |
Experiment description |
Exosomes with immune modulatory features are present in human breast milk. |
Authors |
Admyre C, Johansson SM, Qazi KR, Filen JJ, Lahesmaa R, Norman M, Neve EP, Scheynius A, Gabrielsson S |
Journal name |
JIMMU
|
Publication year |
2007 |
Sample |
Breast milk |
Sample name |
Breast milk - Mature milk |
Isolation/purification methods |
Differential centrifugation Filtration Sucrose density gradient |
Flotation density |
1.10-1.18 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry [QSTAR] Western blotting Immunoelectron Microscopy FACS |
|
|
Protein-protein interactions for CSN1S1 |
|
Pathways in which CSN1S1 is involved |
|
|
|