Gene description for CFAP70
Gene name cilia and flagella associated protein 70
Gene symbol CFAP70
Other names/aliases TTC18
Species Homo sapiens
 Database cross references - CFAP70
ExoCarta ExoCarta_118491
Vesiclepedia VP_118491
Entrez Gene 118491
HGNC 30726
UniProt Q5T0N1  
 CFAP70 identified in sEVs derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for CFAP70
Biological Process
    cilium movement GO:0003341 IBA
    cilium movement GO:0003341 ISS
    cilium assembly GO:0060271 IBA
    cilium assembly GO:0060271 ISS
Subcellular Localization
    axoneme GO:0005930 ISS
    motile cilium GO:0031514 IBA
    ciliary basal body GO:0036064 IDA
    sperm flagellum GO:0036126 IDA
    outer dynein arm GO:0036157 IDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified CFAP70 in sEVs
1
Experiment ID 63
MISEV standards
Biophysical techniques
AQP2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for CFAP70
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HSP90AA1 3320
Cross-Linking-MS (XL-MS) Homo sapiens
2 TRIM21 6737
Affinity Capture-MS Homo sapiens
3 OBSL1 23363
Affinity Capture-MS Homo sapiens
4 KRAS 3845
Negative Genetic Homo sapiens
View the network image/svg+xml
 Pathways in which CFAP70 is involved
No pathways found





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