Gene description for Rhoa
Gene name	ras homolog gene family, member A
Gene symbol	Rhoa
Other names/aliases	Arha Arha1 Arha2
Species	Mus musculus
Database cross references - Rhoa
ExoCarta	ExoCarta_11848
Entrez Gene	11848
UniProt	Q9QUI0
Rhoa identified in exosomes derived from the following tissue/cell type
Basophilic leukemia cells	20424270
Fibroblasts	23260141

Gene ontology annotations for Rhoa

Molecular Function     protein domain specific binding GO:0019904 ISO     GTP binding GO:0005525 ISO     Rho GDP-dissociation inhibitor binding GO:0051022 ISO     nucleotide binding GO:0000166 IEA     GTPase activity GO:0003924 TAS     protein binding GO:0005515 IPI     GDP binding GO:0019003 ISO     myosin binding GO:0017022 ISO Biological Process     apical junction assembly GO:0043297 ISO     actin cytoskeleton organization GO:0030036 IDA     negative regulation of neuron differentiation GO:0045665 ISO     stress fiber assembly GO:0043149 IDA     positive regulation of neuron differentiation GO:0045666 ISO     regulation of neuron projection development GO:0010975 IDA     forebrain radial glial cell differentiation GO:0021861 IMP     regulation of cell migration GO:0030334 ISO     positive regulation of neuron apoptotic process GO:0043525 ISO     cell adhesion GO:0007155 IMP     cell cycle GO:0007049 IEA     trabecula morphogenesis GO:0061383 IMP     regulation of osteoblast proliferation GO:0033688 IMP     androgen receptor signaling pathway GO:0030521 IDA     positive regulation of stress fiber assembly GO:0051496 ISO     small GTPase mediated signal transduction GO:0007264 IEA     cell division GO:0051301 IEA     cell morphogenesis GO:0000902 IGI     negative regulation of cell death GO:0060548 ISO     positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280 ISO     positive regulation of cytokinesis GO:0032467 ISO     Rho protein signal transduction GO:0007266 TAS     cerebral cortex cell migration GO:0021795 IMP     stress-activated protein kinase signaling cascade GO:0031098 ISO     regulation of calcium ion transport GO:0051924 ISO     GTP metabolic process GO:0046039 ISO     cell differentiation GO:0030154 IDA     negative regulation of neuron apoptotic process GO:0043524 IMP     negative chemotaxis GO:0050919 ISO     positive regulation of smooth muscle contraction GO:0045987 ISO     cytoskeleton organization GO:0007010 IMP     negative regulation of I-kappaB kinase/NF-kappaB signaling GO:0043124 ISO     regulation of dendrite development GO:0050773 ISO     positive regulation of actin filament polymerization GO:0030838 ISO     mitotic spindle assembly GO:0090307 ISO     skeletal muscle tissue development GO:0007519 IDA     apolipoprotein A-I-mediated signaling pathway GO:0038027 ISO     positive regulation of podosome assembly GO:0071803 IGI     positive regulation of lipase activity GO:0060193 ISO     regulation of transcription from RNA polymerase II promoter GO:0006357 IDA     positive regulation of cell growth GO:0030307 ISO     cleavage furrow formation GO:0036089 ISO     response to drug GO:0042493 ISO     negative regulation of intracellular steroid hormone receptor signaling pathway GO:0033144 IDA     ossification involved in bone maturation GO:0043931 IMP     cell-matrix adhesion GO:0007160 IDA     regulation of neural precursor cell proliferation GO:2000177 IMP     integrin-mediated signaling pathway GO:0007229 TAS Subcellular Localization     endosome GO:0005768 ISO     plasma membrane GO:0005886 IDA     nucleus GO:0005634 IDA     lamellipodium GO:0030027 IDA     axon GO:0030424 ISO     cytoplasm GO:0005737 ISO     extracellular exosome GO:0070062 ISO     cytoskeleton GO:0005856 IEA     vesicle GO:0031982 ISO     ruffle membrane GO:0032587 IDA     intracellular GO:0005622 IEA     cytosol GO:0005829 TAS     cell cortex GO:0005938 ISO     apical junction complex GO:0043296 ISO     membrane GO:0016020 ISO     mitochondrion GO:0005739 IDA     cell projection GO:0042995 IEA     focal adhesion GO:0005925 ISO