Gene description for GRB2
Gene name growth factor receptor-bound protein 2
Gene symbol GRB2
Other names/aliases ASH
EGFRBP-GRB2
Grb3-3
MST084
MSTP084
NCKAP2
Species Homo sapiens
 Database cross references - GRB2
ExoCarta ExoCarta_2885
Vesiclepedia VP_2885
Entrez Gene 2885
HGNC 4566
MIM 108355
UniProt P62993  
 GRB2 identified in sEVs derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
B cells 20458337    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Pluripotent stem cells 34108659    
Prostate cancer cells 25844599    
Prostate cancer cells 25844599    
T lymphocytes 34108659    
Thymus 23844026    
Urine 19056867    
 Gene ontology annotations for GRB2
Molecular Function
    phosphotyrosine residue binding GO:0001784 IBA
    phosphotyrosine residue binding GO:0001784 IPI
    RNA binding GO:0003723 HDA
    transmembrane receptor protein tyrosine kinase adaptor activity GO:0005068 IEA
    guanyl-nucleotide exchange factor adaptor activity GO:0005091 IDA
    epidermal growth factor receptor binding GO:0005154 IBA
    epidermal growth factor receptor binding GO:0005154 IPI
    neurotrophin TRKA receptor binding GO:0005168 IPI
    protein binding GO:0005515 IPI
    SH3 domain binding GO:0017124 IDA
    protein kinase binding GO:0019901 IPI
    protein phosphatase binding GO:0019903 IEA
    protein-macromolecule adaptor activity GO:0030674 IDA
    identical protein binding GO:0042802 IPI
    insulin receptor substrate binding GO:0043560 IPI
    ephrin receptor binding GO:0046875 IPI
Biological Process
    signal transduction GO:0007165 IBA
    epidermal growth factor receptor signaling pathway GO:0007173 IMP
    epidermal growth factor receptor signaling pathway GO:0007173 TAS
    Ras protein signal transduction GO:0007265 TAS
    insulin receptor signaling pathway GO:0008286 IPI
    fibroblast growth factor receptor signaling pathway GO:0008543 IEA
    Schwann cell development GO:0014044 IEA
    actin cytoskeleton organization GO:0030036 IMP
    positive regulation of actin filament polymerization GO:0030838 IEA
    receptor internalization GO:0031623 IMP
    endodermal cell differentiation GO:0035987 IEA
    T cell activation GO:0042110 IDA
    natural killer cell mediated cytotoxicity GO:0042267 IDA
    myelination GO:0042552 IEA
    signal transduction in response to DNA damage GO:0042770 IMP
    regulation of MAPK cascade GO:0043408 IBA
    negative regulation of natural killer cell mediated cytotoxicity GO:0045953 IDA
    insulin-like growth factor receptor signaling pathway GO:0048009 IEA
    B cell receptor signaling pathway GO:0050853 IEA
    branching involved in labyrinthine layer morphogenesis GO:0060670 IEA
    cellular response to ionizing radiation GO:0071479 IMP
    positive regulation of reactive oxygen species metabolic process GO:2000379 IMP
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IBA
    nucleoplasm GO:0005654 IDA
    nucleolus GO:0005730 IDA
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    endosome GO:0005768 IDA
    Golgi apparatus GO:0005794 IEA
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 TAS
    cell-cell junction GO:0005911 IEA
    cell cortex GO:0005938 IEA
    COP9 signalosome GO:0008180 IBA
    COP9 signalosome GO:0008180 IDA
    vesicle membrane GO:0012506 IEA
    extracellular exosome GO:0070062 HDA
    Grb2-EGFR complex GO:0070436 IDA
 Experiment description of studies that identified GRB2 in sEVs
1
Experiment ID 79
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 80
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 81
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
4
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
9
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
16
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
20
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
21
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
23
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
24
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
27
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
31
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
32
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
33
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
34
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
35
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
36
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
38
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
39
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
40
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
41
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
42
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
43
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
44
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
45
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
46
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for GRB2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 AXL 558
Far Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
PCA Homo sapiens
2 SLC25A13 10165
Affinity Capture-MS Homo sapiens
3 KRT4 3851
Affinity Capture-MS Homo sapiens
4 HDAC4  
Affinity Capture-MS Homo sapiens
5 WDR6 11180
Affinity Capture-MS Homo sapiens
6 AGT 183
Two-hybrid Homo sapiens
7 ETV6  
Affinity Capture-Western Homo sapiens
Far Western Homo sapiens
8 ITIH4 3700
Two-hybrid Homo sapiens
9 SHC1 6464
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 C1orf27 54953
Affinity Capture-MS Homo sapiens
11 DAG1 1605
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
12 AES 166
Two-hybrid Homo sapiens
13 CRK 1398
Reconstituted Complex Homo sapiens
Far Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
14 GC 2638
Two-hybrid Homo sapiens
15 LOC101060321  
Two-hybrid Homo sapiens
16 DNAJB2 3300
Proximity Label-MS Homo sapiens
17 AP2A2 161
Affinity Capture-Western Homo sapiens
18 BRD2  
Affinity Capture-MS Homo sapiens
19 UBC 7316
Two-hybrid Homo sapiens
20 KRT82 3888
Affinity Capture-MS Homo sapiens
21 FHOD1 29109
Two-hybrid Homo sapiens
22 RNF208  
Two-hybrid Homo sapiens
23 VASP 7408
Affinity Capture-MS Homo sapiens
24 FGFR3 2261
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
25 LMO2  
Two-hybrid Homo sapiens
26 PRR22  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
27 DTX3  
Two-hybrid Homo sapiens
28 DARS 1615
Affinity Capture-MS Homo sapiens
29 USP6NL 9712
Reconstituted Complex Homo sapiens
30 AP2A1 160
Affinity Capture-MS Homo sapiens
31 LIME1 54923
Reconstituted Complex Homo sapiens
32 BRCC3 79184
Affinity Capture-MS Homo sapiens
33 CPSF7 79869
Two-hybrid Homo sapiens
34 SRC 6714
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
35 HEXB 3074
Co-fractionation Homo sapiens
36 KDR  
Affinity Capture-Western Homo sapiens
37 KRT1 3848
Affinity Capture-MS Homo sapiens
38 EPS15L1 58513
Affinity Capture-MS Homo sapiens
39 DOCK1 1793
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 LGALS3BP 3959
Affinity Capture-MS Homo sapiens
41 MLXIPL  
Two-hybrid Homo sapiens
42 KIF3A 11127
Two-hybrid Homo sapiens
43 CLASP2 23122
Affinity Capture-MS Homo sapiens
44 INPP5D 3635
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
45 HSPA9 3313
Affinity Capture-MS Homo sapiens
46 DLGAP1  
Two-hybrid Homo sapiens
47 TEC 7006
Affinity Capture-MS Homo sapiens
48 TCP1 6950
Affinity Capture-MS Homo sapiens
49 FASLG 356
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
50 VAV1 7409
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
51 RIN3  
Affinity Capture-MS Homo sapiens
52 WASF1 8936
Two-hybrid Homo sapiens
53 PDGFRB 5159
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
54 DTX1  
Two-hybrid Homo sapiens
55 BRE 9577
Affinity Capture-MS Homo sapiens
56 KRT6A 3853
Affinity Capture-MS Homo sapiens
57 COPB1 1315
Two-hybrid Homo sapiens
58 PPIH 10465
Co-fractionation Homo sapiens
59 SNTA1 6640
Affinity Capture-Western Homo sapiens
60 SH2B2  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
61 UBASH3B 84959
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 ESRRB  
Affinity Capture-MS Homo sapiens
63 MYH9 4627
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
64 KRT9 3857
Affinity Capture-MS Homo sapiens
65 SYNCRIP 10492
Reconstituted Complex Homo sapiens
66 XPOT 11260
Co-fractionation Homo sapiens
67 YWHAQ 10971
Affinity Capture-MS Homo sapiens
68 ENO1 2023
Two-hybrid Homo sapiens
69 DDX17 10521
Two-hybrid Homo sapiens
70 C19orf35  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
71 UBA1 7317
Two-hybrid Homo sapiens
72 SLC1A2  
Two-hybrid Homo sapiens
73 STK32C  
Two-hybrid Homo sapiens
74 SLC25A5 292
Affinity Capture-MS Homo sapiens
75 PIK3CB 5291
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
76 KRT85  
Affinity Capture-MS Homo sapiens
77 HSPA5 3309
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
78 ARHGAP32  
Two-hybrid Homo sapiens
79 RPS19 6223
Affinity Capture-MS Homo sapiens
80 CCDC28B  
Two-hybrid Homo sapiens
81 CD22 933
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
82 CSN2 1447
Two-hybrid Homo sapiens
83 KRT86  
Affinity Capture-MS Homo sapiens
84 KRT35 3886
Affinity Capture-MS Homo sapiens
85 PON2 5445
Two-hybrid Homo sapiens
86 PRKAR1A 5573
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
87 TNFRSF1A 7132
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
88 PIK3AP1  
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
89 CUL3 8452
Affinity Capture-MS Homo sapiens
90 YWHAZ 7534
Affinity Capture-MS Homo sapiens
91 ERBB4 2066
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
92 AEBP1 165
Two-hybrid Homo sapiens
93 ABI3BP 25890
Two-hybrid Homo sapiens
94 PIK3C2B 5287
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
95 KPNA2 3838
Two-hybrid Homo sapiens
96 FN1 2335
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
97 CDC42 998
Two-hybrid Homo sapiens
98 KRT15 3866
Affinity Capture-MS Homo sapiens
99 GPANK1  
Two-hybrid Homo sapiens
100 MYL12B 103910
Affinity Capture-MS Homo sapiens
101 CSF3R  
PCA Homo sapiens
Affinity Capture-Western Homo sapiens
Far Western Homo sapiens
Reconstituted Complex Homo sapiens
Protein-peptide Homo sapiens
102 ESD 2098
Two-hybrid Homo sapiens
103 SPRY1 10252
Affinity Capture-Western Homo sapiens
104 GSTK1 373156
Two-hybrid Homo sapiens
105 SH2B1 25970
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
106 GAB3  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
107 BTG1 694
Two-hybrid Homo sapiens
108 CDKN1B 1027
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
109 KRT19 3880
Affinity Capture-MS Homo sapiens
110 KRT2 3849
Affinity Capture-MS Homo sapiens
111 RASA1 5921
Affinity Capture-Western Homo sapiens
112 FTL 2512
Two-hybrid Homo sapiens
113 VPS28 51160
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
114 RPS27A 6233
Affinity Capture-MS Homo sapiens
115 FASN 2194
Positive Genetic Homo sapiens
116 FAM175B 23172
Affinity Capture-MS Homo sapiens
117 CLPX 10845
Affinity Capture-MS Homo sapiens
118 DAB2 1601
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
119 SHBG 6462
Two-hybrid Homo sapiens
120 GRB2 2885
Co-crystal Structure Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
121 WDR77 79084
Affinity Capture-MS Homo sapiens
122 PLEC 5339
Affinity Capture-MS Homo sapiens
123 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
124 DRD3  
Reconstituted Complex Homo sapiens
125 TCERG1 10915
Two-hybrid Homo sapiens
126 IRS2 8660
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
127 POMP  
Two-hybrid Homo sapiens
128 DPPA4  
Two-hybrid Homo sapiens
129 DCTN2 10540
Two-hybrid Homo sapiens
130 HSP90AA1 3320
Affinity Capture-MS Homo sapiens
131 ROS1  
Co-fractionation Homo sapiens
132 ELMO2 63916
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
133 DYNC1H1 1778
Affinity Capture-MS Homo sapiens
134 NUTM2F  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
135 IK 3550
Two-hybrid Homo sapiens
136 NCL 4691
Two-hybrid Homo sapiens
137 PSMA5 5686
Affinity Capture-MS Homo sapiens
138 PLEKHA7 144100
Two-hybrid Homo sapiens
139 EPHA2 1969
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
140 SOS2 6655
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
141 MAP1A 4130
Two-hybrid Homo sapiens
142 SYN1  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
143 BLNK  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
144 ANXA2 302
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
145 VAV3 10451
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
146 FKBP2 2286
Co-fractionation Homo sapiens
147 ND4 4538
Two-hybrid Homo sapiens
148 KRT7 3855
Affinity Capture-MS Homo sapiens
149 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
150 KRT73 319101
Affinity Capture-MS Homo sapiens
151 Gab2  
Affinity Capture-Western Mus musculus
152 HSPA6 3310
Co-fractionation Homo sapiens
153 PTPN22  
Affinity Capture-Western Homo sapiens
154 TSC2 7249
Two-hybrid Homo sapiens
155 DOK3 79930
Affinity Capture-MS Homo sapiens
156 ADRB2  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
157 GFAP 2670
Affinity Capture-MS Homo sapiens
158 HSP90AB1 3326
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
159 Shc1  
Affinity Capture-Western Mus musculus
160 PSMD11 5717
Affinity Capture-MS Homo sapiens
161 RALGPS1  
Affinity Capture-Western Homo sapiens
162 ARHGEF35  
Affinity Capture-MS Homo sapiens
163 IL6ST 3572
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
164 HP 3240
Two-hybrid Homo sapiens
165 DIAPH1 1729
Affinity Capture-MS Homo sapiens
166 HELZ 9931
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
167 C21orf91  
Two-hybrid Homo sapiens
168 MUC1 4582
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
169 NPM1 4869
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
170 MAP4K5 11183
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
171 KHDRBS1 10657
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
172 SYK 6850
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
173 MICAL1 64780
Reconstituted Complex Homo sapiens
174 AGER 177
Affinity Capture-MS Homo sapiens
175 PLCG1 5335
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
176 HIST4H4 121504
Affinity Capture-MS Homo sapiens
177 YWHAH 7533
Affinity Capture-MS Homo sapiens
178 VCAM1 7412
Affinity Capture-MS Homo sapiens
179 FGD6  
Affinity Capture-MS Homo sapiens
180 CD28  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
181 HSD17B4 3295
Affinity Capture-MS Homo sapiens
182 SYNM 23336
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
183 USP53 54532
Two-hybrid Homo sapiens
184 SPATA2L  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
185 YWHAB 7529
Affinity Capture-MS Homo sapiens
186 CCT2 10576
Affinity Capture-MS Homo sapiens
187 PSMC2 5701
Affinity Capture-MS Homo sapiens
188 PPP5C 5536
Affinity Capture-MS Homo sapiens
189 TTYH2 94015
Affinity Capture-MS Homo sapiens
190 SKAP1 8631
Affinity Capture-Western Homo sapiens
191 DRG1 4733
Affinity Capture-MS Homo sapiens
192 PSMD14 10213
Affinity Capture-MS Homo sapiens
193 CBL 867
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
FRET Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Far Western Homo sapiens
Reconstituted Complex Homo sapiens
Far Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Co-purification Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
194 SNRNP200 23020
Two-hybrid Homo sapiens
195 TUBA1C 84790
Affinity Capture-MS Homo sapiens
196 PBXIP1 57326
Two-hybrid Homo sapiens
197 CD164 8763
Two-hybrid Homo sapiens
198 HDGFRP3 50810
Affinity Capture-MS Homo sapiens
199 SLX1A  
Two-hybrid Homo sapiens
200 PTK2B 2185
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
201 S100A8 6279
Affinity Capture-MS Homo sapiens
202 KRT14 3861
Affinity Capture-MS Homo sapiens
203 AGR2 10551
Two-hybrid Homo sapiens
204 PHACTR4 65979
Two-hybrid Homo sapiens
205 RAPGEF1 2889
Affinity Capture-Western Homo sapiens
Far Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
206 GAREM  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
207 PRKAB1 5564
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
208 ZNF474  
Two-hybrid Homo sapiens
209 NKD2 85409
Two-hybrid Homo sapiens
210 CYLD  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
211 PDE4D  
Far Western Homo sapiens
212 HNRNPD 3184
Affinity Capture-MS Homo sapiens
213 LAT 27040
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
214 PTPN11 5781
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Far Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
215 TUBB 203068
Affinity Capture-MS Homo sapiens
216 SYNJ2 8871
Two-hybrid Homo sapiens
217 NKX2-5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
218 MFAP4 4239
Affinity Capture-MS Homo sapiens
219 IKZF3  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
220 TP53BP2  
Two-hybrid Homo sapiens
221 YLPM1 56252
Two-hybrid Homo sapiens
222 TUBB4B 10383
Affinity Capture-MS Homo sapiens
223 EGFR 1956
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Negative Genetic Homo sapiens
PCA Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
224 FABP1 2168
Two-hybrid Homo sapiens
225 PTK2 5747
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
226 FUS 2521
Affinity Capture-MS Homo sapiens
227 LAT2 7462
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
228 FTH1 2495
Two-hybrid Homo sapiens
229 SPTBN1 6711
Two-hybrid Homo sapiens
230 GAB1  
Two-hybrid Homo sapiens
Far Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
231 DUSP13  
Affinity Capture-MS Homo sapiens
232 ZMYM6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
233 MYC  
Affinity Capture-MS Homo sapiens
234 IRF5  
Affinity Capture-MS Homo sapiens
235 JAK1 3716
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
236 RARS 5917
Affinity Capture-MS Homo sapiens
237 ARHGEF5  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
238 MET 4233
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
239 IL2RB  
Reconstituted Complex Homo sapiens
240 WDR44 54521
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
241 GJA9  
Affinity Capture-MS Homo sapiens
242 ANKRD23 200539
Two-hybrid Homo sapiens
243 POLR1D 51082
Two-hybrid Homo sapiens
244 HUWE1 10075
Affinity Capture-MS Homo sapiens
245 CKS2  
Two-hybrid Homo sapiens
246 KRT18 3875
Affinity Capture-MS Homo sapiens
247 TFG 10342
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
248 SH3PXD2B 285590
Affinity Capture-MS Homo sapiens
249 PRRC2A 7916
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
250 PARP1 142
Affinity Capture-MS Homo sapiens
251 WIPF3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
252 HOMEZ  
Two-hybrid Homo sapiens
253 PDCD6IP 10015
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
254 LAX1  
Affinity Capture-Western Homo sapiens
255 PPP2R2A 5520
Affinity Capture-MS Homo sapiens
256 FLT4  
Reconstituted Complex Homo sapiens
257 SF3B4 10262
Two-hybrid Homo sapiens
258 RIF1  
Two-hybrid Homo sapiens
259 SOS1 6654
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Far Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
260 LY6G6F 259215
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
261 FAM109A  
Two-hybrid Homo sapiens
262 DDIT4L  
Two-hybrid Homo sapiens
263 HNRNPK 3190
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
264 NEFH 4744
Affinity Capture-MS Homo sapiens
265 HSPA1B 3304
Affinity Capture-MS Homo sapiens
266 EEF1A1P5 158078
Affinity Capture-MS Homo sapiens
267 ERRFI1 54206
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
268 C16orf72 29035
Affinity Capture-MS Homo sapiens
269 DNAJB4 11080
Proximity Label-MS Homo sapiens
270 B2M 567
Two-hybrid Homo sapiens
271 TRIB3  
Two-hybrid Homo sapiens
272 STARD10 10809
Affinity Capture-MS Homo sapiens
273 KRAS 3845
Synthetic Lethality Homo sapiens
Synthetic Lethality Homo sapiens
274 SH3KBP1 30011
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
275 PHC2  
Two-hybrid Homo sapiens
276 HUNK  
Affinity Capture-MS Homo sapiens
277 BCAR1 9564
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
278 JAK2 3717
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
279 VIM 7431
Two-hybrid Homo sapiens
280 SH3PXD2A 9644
Affinity Capture-MS Homo sapiens
281 RBP4 5950
Two-hybrid Homo sapiens
282 LNX1  
Two-hybrid Homo sapiens
283 NAP1L5  
Two-hybrid Homo sapiens
284 ATP5A1 498
Co-fractionation Homo sapiens
285 MED28  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
286 SHC2 25759
Affinity Capture-Western Homo sapiens
287 AP2S1 1175
Affinity Capture-MS Homo sapiens
288 HNRNPC 3183
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
289 PPP3CA 5530
Two-hybrid Homo sapiens
290 SH2D5  
Affinity Capture-MS Homo sapiens
291 ITGA2B 3674
Reconstituted Complex Homo sapiens
292 EEF1G 1937
Affinity Capture-MS Homo sapiens
293 WIPF2 147179
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
294 THEMIS 387357
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
295 PRR5-ARHGAP8  
Two-hybrid Homo sapiens
296 KRT17 3872
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
297 YWHAE 7531
Affinity Capture-MS Homo sapiens
298 REL 5966
Two-hybrid Homo sapiens
299 GLS2 27165
Affinity Capture-MS Homo sapiens
300 EPS15 2060
Far Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
301 FLT3  
Affinity Capture-Western Homo sapiens
302 SHB 6461
Affinity Capture-Western Homo sapiens
303 EPS8 2059
Two-hybrid Homo sapiens
304 NCKIPSD 51517
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
305 RET 5979
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
306 PTPN1 5770
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
307 MAP4K3 8491
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
308 FAU 2197
Affinity Capture-MS Homo sapiens
309 RUVBL1 8607
Affinity Capture-MS Homo sapiens
310 MLLT4 4301
Affinity Capture-MS Homo sapiens
311 PTPN12 5782
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
312 MCM2 4171
Affinity Capture-MS Homo sapiens
313 AHSG 197
Two-hybrid Homo sapiens
314 IQGAP1 8826
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
315 PSME1 5720
Affinity Capture-MS Homo sapiens
316 SF3A2 8175
Two-hybrid Homo sapiens
317 KRT5 3852
Affinity Capture-MS Homo sapiens
318 ITGA4 3676
Affinity Capture-MS Homo sapiens
319 EPOR  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
320 ATG16L1 55054
Affinity Capture-MS Homo sapiens
321 ARID5A  
Two-hybrid Homo sapiens
322 GAREML  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
323 APOH 350
Two-hybrid Homo sapiens
324 NCK1 4690
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
325 CTAGE5 4253
Two-hybrid Homo sapiens
326 NIF3L1 60491
Two-hybrid Homo sapiens
327 HSPA8 3312
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
328 MAP2 4133
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
329 UBR4 23352
Affinity Capture-MS Homo sapiens
330 PNMA5 114824
Two-hybrid Homo sapiens
331 PRAP1  
Two-hybrid Homo sapiens
332 IRS4 8471
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
333 MYO18A 399687
Two-hybrid Homo sapiens
334 KIT 3815
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Protein-peptide Homo sapiens
Reconstituted Complex Homo sapiens
335 FOXA1  
Affinity Capture-MS Homo sapiens
336 USP12 219333
Proximity Label-MS Homo sapiens
337 SOCS7  
Two-hybrid Homo sapiens
338 TBC1D3B  
Two-hybrid Homo sapiens
339 RACGAP1 29127
Affinity Capture-MS Homo sapiens
340 SKAP2 8935
Affinity Capture-MS Homo sapiens
341 USP8 9101
Reconstituted Complex Homo sapiens
342 MAPT  
Protein-peptide Homo sapiens
343 PTPRE 5791
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
344 SH3BP2  
Reconstituted Complex Homo sapiens
345 NTRK1 4914
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
346 KRT34  
Affinity Capture-MS Homo sapiens
347 ACTB 60
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
348 REPS2  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
349 PIK3R1 5295
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
350 VAV2 7410
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
351 STAMBP 10617
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
352 MYL12A 10627
Affinity Capture-MS Homo sapiens
353 ACTG1 71
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
354 HCLS1 3059
Reconstituted Complex Homo sapiens
355 ASAP2 8853
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
356 MAP4K1  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
357 ARHGAP17 55114
Reconstituted Complex Homo sapiens
358 NEU3  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
359 PRRG4  
Reconstituted Complex Homo sapiens
360 RBBP6 5930
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
361 SYNJ1 8867
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
362 ALAS2  
Two-hybrid Homo sapiens
363 MEI4  
Two-hybrid Homo sapiens
364 Mta3  
Reconstituted Complex Mus musculus
365 OCRL 4952
Reconstituted Complex Homo sapiens
366 AHNAK 79026
Affinity Capture-MS Homo sapiens
367 TAB1 10454
Affinity Capture-MS Homo sapiens
368 PTPRA 5786
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
369 PDGFRA 5156
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
370 SIRPA 140885
Affinity Capture-MS Homo sapiens
371 EPPK1 83481
Affinity Capture-MS Homo sapiens
372 SNX18 112574
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
373 CASP2  
Two-hybrid Homo sapiens
374 PTEN 5728
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
375 COX6A1  
Two-hybrid Homo sapiens
376 H1F0 3005
Two-hybrid Homo sapiens
377 NADK 65220
Two-hybrid Homo sapiens
378 CYFIP2 26999
Affinity Capture-MS Homo sapiens
379 RBM33  
Two-hybrid Homo sapiens
380 AP2M1 1173
Affinity Capture-MS Homo sapiens
381 RADIL  
Affinity Capture-MS Homo sapiens
382 LRRK1 79705
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
383 PIK3CA 5290
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
384 SH3D19 152503
Two-hybrid Homo sapiens
385 PTPN23 25930
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
386 AMBP 259
Two-hybrid Homo sapiens
387 EFHC2  
Two-hybrid Homo sapiens
388 HSPD1 3329
Affinity Capture-MS Homo sapiens
389 ASAP1 50807
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
390 CSF1R  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
391 MVB12A 93343
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
392 ADAM10 102
Affinity Capture-Western Homo sapiens
393 ARHGEF7 8874
Affinity Capture-MS Homo sapiens
394 DNAJC4  
Proximity Label-MS Homo sapiens
395 MED19  
Two-hybrid Homo sapiens
396 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
397 CCT8 10694
Affinity Capture-MS Homo sapiens
398 SLC25A6 293
Affinity Capture-MS Homo sapiens
399 AP4S1 11154
Two-hybrid Homo sapiens
400 CUTA 51596
Two-hybrid Homo sapiens
401 TUBA4B 80086
Affinity Capture-MS Homo sapiens
402 DOCK5 80005
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
403 KRT10 3858
Affinity Capture-MS Homo sapiens
404 INCA1  
Two-hybrid Homo sapiens
405 HIPK3 10114
Two-hybrid Homo sapiens
406 ABL1 25
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
407 INSR 3643
Affinity Capture-Western Homo sapiens
408 S100A9 6280
Affinity Capture-MS Homo sapiens
409 GAB2 9846
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
410 CCT7 10574
Affinity Capture-MS Homo sapiens
411 BPGM 669
Two-hybrid Homo sapiens
412 LTK 4058
Affinity Capture-Western Homo sapiens
413 BABAM1 29086
Affinity Capture-MS Homo sapiens
414 NFYB  
Two-hybrid Homo sapiens
415 FRS2 10818
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
416 FLNA 2316
Affinity Capture-MS Homo sapiens
417 LCP2 3937
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
418 SERBP1 26135
Affinity Capture-MS Homo sapiens
419 GHR  
Reconstituted Complex Homo sapiens
420 SH2D4A 63898
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
421 AR 367
Reconstituted Complex Homo sapiens
422 RAC1 5879
Affinity Capture-MS Homo sapiens
423 VPS37B 79720
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
424 SELL 6402
Affinity Capture-Western Homo sapiens
425 ALOX5  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
426 EP300 2033
Two-hybrid Homo sapiens
427 CASC3  
Two-hybrid Homo sapiens
428 BCR 613
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Far Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
429 DNAJC22  
Proximity Label-MS Homo sapiens
430 UBE2H 7328
Affinity Capture-MS Homo sapiens
431 RIT1 6016
Negative Genetic Homo sapiens
432 OTUD5 55593
Affinity Capture-MS Homo sapiens
433 ABL2  
Reconstituted Complex Homo sapiens
434 AP2B1 163
Affinity Capture-MS Homo sapiens
435 CCT3 7203
Affinity Capture-MS Homo sapiens
436 ZNF341  
Two-hybrid Homo sapiens
437 DOCK4 9732
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
438 CSK 1445
Affinity Capture-MS Homo sapiens
439 DUSP8  
Affinity Capture-MS Homo sapiens
440 EPHB1 2047
Two-hybrid Homo sapiens
441 USP5 8078
Co-fractionation Homo sapiens
442 CSRP1 1465
Affinity Capture-MS Homo sapiens
443 CD2AP 23607
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
444 HSPA1L 3305
Affinity Capture-MS Homo sapiens
445 TSG101 7251
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
446 SOCS1  
Reconstituted Complex Homo sapiens
447 CCT4 10575
Affinity Capture-MS Homo sapiens
448 PLEKHA2 59339
Affinity Capture-MS Homo sapiens
449 SNRPD2 6633
Affinity Capture-MS Homo sapiens
450 ABI3 51225
Two-hybrid Homo sapiens
451 PPP1CC 5501
Affinity Capture-MS Homo sapiens
452 WAS 7454
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
453 RPS20 6224
Affinity Capture-MS Homo sapiens
454 RNF10  
Two-hybrid Homo sapiens
455 PSTPIP2 9050
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
456 ZAP70 7535
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
457 IMPDH2 3615
Affinity Capture-MS Homo sapiens
458 HGS 9146
Affinity Capture-MS Homo sapiens
459 CALM3 808
Affinity Capture-MS Homo sapiens
460 MST1R 4486
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
461 YWHAG 7532
Affinity Capture-MS Homo sapiens
462 ATP8  
Two-hybrid Homo sapiens
463 RAD51  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
464 SHC4  
Affinity Capture-Western Homo sapiens
465 ALK 238
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
466 TULP3 7289
Affinity Capture-MS Homo sapiens
467 WASL 8976
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
468 KRT83  
Affinity Capture-MS Homo sapiens
469 KIAA1549L 25758
Two-hybrid Homo sapiens
470 DNM1 1759
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Far Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
471 CBLB 868
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
472 ERBB2 2064
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
473 ARHGAP9 64333
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
474 WDR1 9948
Two-hybrid Homo sapiens
475 WIPF1 7456
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
476 KRT8 3856
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
477 PPP1CA 5499
Affinity Capture-MS Homo sapiens
478 ARHGAP12  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
479 TCEAL8  
Two-hybrid Homo sapiens
480 PLXNB1 5364
Affinity Capture-Western Homo sapiens
481 PDE6G  
Reconstituted Complex Homo sapiens
482 ERBB3 2065
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
483 SMU1 55234
Affinity Capture-MS Homo sapiens
484 A2M 2
Two-hybrid Homo sapiens
485 CCT5 22948
Affinity Capture-MS Homo sapiens
486 TOM1L1 10040
Reconstituted Complex Homo sapiens
487 HTT 3064
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
488 PAG1 55824
Reconstituted Complex Homo sapiens
489 GIT1 28964
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
490 Synj1 85238
Reconstituted Complex Rattus norvegicus
491 SPRY4 81848
Affinity Capture-Western Homo sapiens
492 CRKL 1399
Affinity Capture-Western Homo sapiens
493 ACTL6A 86
Affinity Capture-MS Homo sapiens
494 DCTN1 1639
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
495 PEAK1 79834
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
496 FH 2271
Two-hybrid Homo sapiens
497 C12orf10 60314
Two-hybrid Homo sapiens
498 ITK 3702
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
499 MYH11 4629
Two-hybrid Homo sapiens
500 BTK 695
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
501 DNM2 1785
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
502 ITCH 83737
Co-fractionation Homo sapiens
503 CEBPA  
Protein-peptide Homo sapiens
504 DNAJB11 51726
Two-hybrid Homo sapiens
505 EEF1D 1936
Affinity Capture-MS Homo sapiens
506 BAG3 9531
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
507 CLU 1191
Two-hybrid Homo sapiens
508 HIST1H3A 8350
Affinity Capture-MS Homo sapiens
509 KRT33B 3884
Affinity Capture-MS Homo sapiens
510 PTPN6 5777
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
511 PSMD13 5719
Affinity Capture-MS Homo sapiens
512 NCKAP1 10787
Affinity Capture-MS Homo sapiens
513 KRT32  
Affinity Capture-MS Homo sapiens
514 ZBTB12  
Two-hybrid Homo sapiens
515 CTTN 2017
Affinity Capture-MS Homo sapiens
516 MAP3K1 4214
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
517 CD59 966
Affinity Capture-MS Homo sapiens
518 ECHS1 1892
Two-hybrid Homo sapiens
519 APCS 325
Two-hybrid Homo sapiens
520 LZTS2 84445
Two-hybrid Homo sapiens
521 MYCN  
Affinity Capture-MS Homo sapiens
522 KIRREL 55243
Affinity Capture-MS Homo sapiens
523 SLAIN2  
Affinity Capture-MS Homo sapiens
524 DCUN1D1 54165
Affinity Capture-MS Homo sapiens
525 FABP5 2171
Co-fractionation Homo sapiens
526 MSI2 124540
Two-hybrid Homo sapiens
527 TRIM27  
Two-hybrid Homo sapiens
528 C1orf94  
Two-hybrid Homo sapiens
529 ZBTB7B  
Two-hybrid Homo sapiens
530 CLTC 1213
Affinity Capture-MS Homo sapiens
531 HNRNPU 3192
Affinity Capture-MS Homo sapiens
532 POLR2A 5430
Two-hybrid Homo sapiens
533 HSPG2 3339
Affinity Capture-MS Homo sapiens
534 KRT16 3868
Affinity Capture-MS Homo sapiens
535 ARAP1 116985
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
536 SHKBP1  
Reconstituted Complex Homo sapiens
537 SS18  
Two-hybrid Homo sapiens
538 TNK2 10188
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
539 SHANK3 85358
Two-hybrid Homo sapiens
540 SPRY2 10253
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
541 KRT36 8689
Affinity Capture-MS Homo sapiens
542 GGN  
Two-hybrid Homo sapiens
543 C21orf58  
Two-hybrid Homo sapiens
544 VPS37C 55048
Two-hybrid Homo sapiens
545 PRNP 5621
Affinity Capture-MS Homo sapiens
546 INPPL1 3636
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
547 WBP11  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
548 STRADB  
Two-hybrid Homo sapiens
549 CFH 3075
Two-hybrid Homo sapiens
550 SH2B3  
Affinity Capture-Western Homo sapiens
551 UBA52 7311
Two-hybrid Homo sapiens
552 DNAJA3 9093
Two-hybrid Homo sapiens
553 CBR1 873
Affinity Capture-MS Homo sapiens
554 TRAT1 50852
Reconstituted Complex Homo sapiens
555 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
556 NISCH 11188
Affinity Capture-MS Homo sapiens
557 EPB41L2 2037
Co-fractionation Homo sapiens
558 ADAM15 8751
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
559 KRT81  
Affinity Capture-MS Homo sapiens
560 TF 7018
Two-hybrid Homo sapiens
561 Mta1  
Reconstituted Complex Mus musculus
562 CNOT1 23019
Affinity Capture-MS Homo sapiens
563 DOK1 1796
Affinity Capture-Western Homo sapiens
564 ZNF620  
Two-hybrid Homo sapiens
565 CAD 790
Affinity Capture-MS Homo sapiens
566 MAPK9 5601
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
567 PXN 5829
Reconstituted Complex Homo sapiens
568 DNM3 26052
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
569 PTPRJ 5795
Affinity Capture-MS Homo sapiens
570 PIK3R2 5296
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
571 IGF2BP1 10642
Affinity Capture-MS Homo sapiens
572 DRD4  
Reconstituted Complex Homo sapiens
573 C9orf72  
Affinity Capture-MS Homo sapiens
574 ARHGAP35 2909
Affinity Capture-Western Homo sapiens
575 PTPN18 26469
Affinity Capture-MS Homo sapiens
576 IRS1 3667
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
577 GAPDH 2597
Affinity Capture-MS Homo sapiens
578 KIAA0408  
Two-hybrid Homo sapiens
579 PIK3R3 8503
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which GRB2 is involved
PathwayEvidenceSource
Activated NTRK2 signals through FRS2 and FRS3 TAS Reactome
Activated NTRK2 signals through FRS2 and FRS3 IEA Reactome
Activated NTRK2 signals through PI3K IEA Reactome
Activated NTRK2 signals through RAS IEA Reactome
Activated NTRK3 signals through RAS IEA Reactome
Adaptive Immune System TAS Reactome
Adaptive Immune System IEA Reactome
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers TAS Reactome
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers IEA Reactome
Axon guidance TAS Reactome
Bacterial Infection Pathways IEA Reactome
Bacterial Infection Pathways TAS Reactome
Cargo recognition for clathrin-mediated endocytosis TAS Reactome
CD28 co-stimulation TAS Reactome
CD28 dependent Vav1 pathway TAS Reactome
Cell surface interactions at the vascular wall TAS Reactome
Cell-Cell communication TAS Reactome
Clathrin-mediated endocytosis TAS Reactome
Constitutive Signaling by Aberrant PI3K in Cancer TAS Reactome
Constitutive Signaling by EGFRvIII TAS Reactome
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants TAS Reactome
Constitutive Signaling by Overexpressed ERBB2 TAS Reactome
Costimulation by the CD28 family TAS Reactome
Cytokine Signaling in Immune system IEA Reactome
Cytokine Signaling in Immune system TAS Reactome
DAP12 interactions TAS Reactome
DAP12 signaling TAS Reactome
Developmental Biology TAS Reactome
Disease TAS Reactome
Disease IEA Reactome
Diseases of signal transduction by growth factor receptors and second messengers IEA Reactome
Diseases of signal transduction by growth factor receptors and second messengers TAS Reactome
Downstream signal transduction TAS Reactome
Downstream signaling of activated FGFR1 TAS Reactome
Downstream signaling of activated FGFR2 TAS Reactome
Downstream signaling of activated FGFR3 TAS Reactome
Downstream signaling of activated FGFR4 TAS Reactome
EGFR downregulation TAS Reactome
EGFR Transactivation by Gastrin TAS Reactome
Erythropoietin activates RAS IEA Reactome
Erythropoietin activates RAS TAS Reactome
Fc epsilon receptor (FCERI) signaling TAS Reactome
Fc epsilon receptor (FCERI) signaling IEA Reactome
FCERI mediated Ca+2 mobilization IEA Reactome
FCERI mediated Ca+2 mobilization TAS Reactome
FCERI mediated MAPK activation TAS Reactome
Fcgamma receptor (FCGR) dependent phagocytosis TAS Reactome
Fcgamma receptor (FCGR) dependent phagocytosis IEA Reactome
FCGR3A-mediated phagocytosis TAS Reactome
FCGR3A-mediated phagocytosis IEA Reactome
FGFR1 mutant receptor activation TAS Reactome
FLT3 Signaling IEA Reactome
FLT3 Signaling TAS Reactome
FLT3 signaling in disease IEA Reactome
FLT3 signaling in disease TAS Reactome
FRS-mediated FGFR1 signaling TAS Reactome
FRS-mediated FGFR2 signaling TAS Reactome
FRS-mediated FGFR3 signaling TAS Reactome
FRS-mediated FGFR4 signaling TAS Reactome
G alpha (q) signalling events TAS Reactome
GAB1 signalosome TAS Reactome
Gastrin-CREB signalling pathway via PKC and MAPK TAS Reactome
GPCR downstream signalling TAS Reactome
GRB2 events in EGFR signaling TAS Reactome
GRB2 events in ERBB2 signaling TAS Reactome
GRB2 events in ERBB2 signaling IEA Reactome
GRB2:SOS provides linkage to MAPK signaling for Integrins TAS Reactome
Hemostasis TAS Reactome
IGF1R signaling cascade TAS Reactome
IGF1R signaling cascade IEA Reactome
Immune System TAS Reactome
Immune System IEA Reactome
Infectious disease TAS Reactome
Infectious disease IEA Reactome
InlB-mediated entry of Listeria monocytogenes into host cell IEA Reactome
InlB-mediated entry of Listeria monocytogenes into host cell TAS Reactome
Innate Immune System TAS Reactome
Innate Immune System IEA Reactome
Insulin receptor signalling cascade TAS Reactome
Insulin receptor signalling cascade IEA Reactome
Integrin signaling TAS Reactome
Interleukin receptor SHC signaling TAS Reactome
Interleukin-15 signaling TAS Reactome
Interleukin-15 signaling IEA Reactome
Interleukin-2 family signaling TAS Reactome
Interleukin-2 family signaling IEA Reactome
Interleukin-3, Interleukin-5 and GM-CSF signaling TAS Reactome
Interleukin-3, Interleukin-5 and GM-CSF signaling IEA Reactome
Intracellular signaling by second messengers TAS Reactome
IRS-mediated signalling TAS Reactome
IRS-mediated signalling IEA Reactome
IRS-related events triggered by IGF1R TAS Reactome
IRS-related events triggered by IGF1R IEA Reactome
Leishmania infection TAS Reactome
Leishmania infection IEA Reactome
Leishmania phagocytosis TAS Reactome
Leishmania phagocytosis IEA Reactome
Listeria monocytogenes entry into host cells IEA Reactome
Listeria monocytogenes entry into host cells TAS Reactome
MAPK family signaling cascades TAS Reactome
MAPK1/MAPK3 signaling TAS Reactome
Membrane Trafficking TAS Reactome
MET activates PI3K/AKT signaling TAS Reactome
MET activates PTPN11 TAS Reactome
MET activates RAP1 and RAC1 TAS Reactome
MET activates RAS signaling TAS Reactome
MET promotes cell motility TAS Reactome
MET receptor recycling TAS Reactome
NCAM signaling for neurite out-growth TAS Reactome
Negative regulation of FGFR1 signaling TAS Reactome
Negative regulation of FGFR2 signaling TAS Reactome
Negative regulation of FGFR3 signaling TAS Reactome
Negative regulation of FGFR4 signaling TAS Reactome
Negative regulation of MET activity TAS Reactome
Negative regulation of the PI3K/AKT network TAS Reactome
Nervous system development TAS Reactome
Parasite infection TAS Reactome
Parasite infection IEA Reactome
Parasitic Infection Pathways TAS Reactome
Parasitic Infection Pathways IEA Reactome
PI-3K cascade:FGFR1 TAS Reactome
PI-3K cascade:FGFR2 TAS Reactome
PI-3K cascade:FGFR3 TAS Reactome
PI-3K cascade:FGFR4 TAS Reactome
PI3K Cascade TAS Reactome
PI3K events in ERBB2 signaling TAS Reactome
PI3K/AKT Signaling in Cancer TAS Reactome
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling TAS Reactome
PIP3 activates AKT signaling TAS Reactome
Platelet activation, signaling and aggregation TAS Reactome
Platelet Aggregation (Plug Formation) TAS Reactome
Potential therapeutics for SARS TAS Reactome
RAF/MAP kinase cascade TAS Reactome
Regulation of actin dynamics for phagocytic cup formation TAS Reactome
Regulation of actin dynamics for phagocytic cup formation IEA Reactome
Regulation of KIT signaling TAS Reactome
Regulation of signaling by CBL TAS Reactome
Regulation of signaling by CBL IEA Reactome
RET signaling TAS Reactome
RHO GTPase cycle TAS Reactome
RHO GTPase Effectors TAS Reactome
RHO GTPase Effectors IEA Reactome
RHO GTPases Activate WASPs and WAVEs TAS Reactome
RHO GTPases Activate WASPs and WAVEs IEA Reactome
RHOU GTPase cycle TAS Reactome
Role of LAT2/NTAL/LAB on calcium mobilization TAS Reactome
Role of LAT2/NTAL/LAB on calcium mobilization IEA Reactome
SARS-CoV Infections TAS Reactome
SHC-mediated cascade:FGFR1 TAS Reactome
SHC-mediated cascade:FGFR2 TAS Reactome
SHC-mediated cascade:FGFR3 TAS Reactome
SHC-mediated cascade:FGFR4 TAS Reactome
SHC-related events triggered by IGF1R TAS Reactome
SHC-related events triggered by IGF1R IEA Reactome
SHC1 events in EGFR signaling TAS Reactome
SHC1 events in ERBB2 signaling IEA Reactome
SHC1 events in ERBB4 signaling TAS Reactome
Signal attenuation TAS Reactome
Signal regulatory protein family interactions TAS Reactome
Signal Transduction TAS Reactome
Signal Transduction IEA Reactome
Signaling by ALK fusions and activated point mutants TAS Reactome
Signaling by ALK in cancer TAS Reactome
Signaling by CSF1 (M-CSF) in myeloid cells IEA Reactome
Signaling by CSF3 (G-CSF) IEA Reactome
Signaling by CSF3 (G-CSF) TAS Reactome
Signaling by cytosolic FGFR1 fusion mutants TAS Reactome
Signaling by EGFR TAS Reactome
Signaling by EGFR in Cancer TAS Reactome
Signaling by EGFRvIII in Cancer TAS Reactome
Signaling by ERBB2 TAS Reactome
Signaling by ERBB2 IEA Reactome
Signaling by ERBB2 ECD mutants TAS Reactome
Signaling by ERBB2 in Cancer TAS Reactome
Signaling by ERBB2 KD Mutants TAS Reactome
Signaling by ERBB2 TMD/JMD mutants TAS Reactome
Signaling by ERBB4 TAS Reactome
Signaling by Erythropoietin IEA Reactome
Signaling by Erythropoietin TAS Reactome
Signaling by FGFR TAS Reactome
Signaling by FGFR in disease TAS Reactome
Signaling by FGFR1 TAS Reactome
Signaling by FGFR1 in disease TAS Reactome
Signaling by FGFR2 TAS Reactome
Signaling by FGFR2 in disease TAS Reactome
Signaling by FGFR3 TAS Reactome
Signaling by FGFR3 in disease TAS Reactome
Signaling by FGFR4 TAS Reactome
Signaling by FGFR4 in disease TAS Reactome
Signaling by FLT3 fusion proteins IEA Reactome
Signaling by FLT3 fusion proteins TAS Reactome
Signaling by FLT3 ITD and TKD mutants TAS Reactome
Signaling by FLT3 ITD and TKD mutants IEA Reactome
Signaling by GPCR TAS Reactome
Signaling by Insulin receptor TAS Reactome
Signaling by Insulin receptor IEA Reactome
Signaling by Interleukins TAS Reactome
Signaling by Interleukins IEA Reactome
Signaling by KIT in disease TAS Reactome
Signaling by Ligand-Responsive EGFR Variants in Cancer TAS Reactome
Signaling by LTK TAS Reactome
Signaling by MET TAS Reactome
Signaling by NTRK1 (TRKA) TAS Reactome
Signaling by NTRK1 (TRKA) IEA Reactome
Signaling by NTRK2 (TRKB) TAS Reactome
Signaling by NTRK2 (TRKB) IEA Reactome
Signaling by NTRK3 (TRKC) IEA Reactome
Signaling by NTRKs TAS Reactome
Signaling by NTRKs IEA Reactome
Signaling by PDGF TAS Reactome
Signaling by PDGFR in disease TAS Reactome
Signaling by PDGFRA extracellular domain mutants TAS Reactome
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants TAS Reactome
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants TAS Reactome
Signaling by Receptor Tyrosine Kinases TAS Reactome
Signaling by Receptor Tyrosine Kinases IEA Reactome
Signaling by Rho GTPases TAS Reactome
Signaling by Rho GTPases IEA Reactome
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 TAS Reactome
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 IEA Reactome
Signaling by SCF-KIT TAS Reactome
Signaling by the B Cell Receptor (BCR) TAS Reactome
Signaling by the B Cell Receptor (BCR) IEA Reactome
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) TAS Reactome
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) IEA Reactome
Signalling to ERKs TAS Reactome
Signalling to ERKs IEA Reactome
Signalling to RAS TAS Reactome
Signalling to RAS IEA Reactome
SOS-mediated signalling TAS Reactome
SOS-mediated signalling IEA Reactome
Spry regulation of FGF signaling TAS Reactome
STAT5 Activation IEA Reactome
STAT5 activation downstream of FLT3 ITD mutants TAS Reactome
Tie2 Signaling TAS Reactome
Vesicle-mediated transport TAS Reactome
Viral Infection Pathways TAS Reactome





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