Gene description for Loxl2
Gene name	lysyl oxidase-like 2
Gene symbol	Loxl2
Other names/aliases	1110004B06Rik 4930526G11Rik 9430067E15Rik
Species	Mus musculus
Database cross references - Loxl2
ExoCarta	ExoCarta_94352
Vesiclepedia	VP_94352
Entrez Gene	94352
UniProt	P58022
Loxl2 identified in sEVs derived from the following tissue/cell type
Fibroblasts	23260141
Melanoma cells	34957415
Melanoma cells	34957415

Gene ontology annotations for Loxl2

Molecular Function     protein-lysine 6-oxidase activity GO:0004720 IBA     protein-lysine 6-oxidase activity GO:0004720 ISO     protein-lysine 6-oxidase activity GO:0004720 ISS     copper ion binding GO:0005507 ISO     copper ion binding GO:0005507 ISS     calcium ion binding GO:0005509 ISO     calcium ion binding GO:0005509 ISS     oligosaccharide binding GO:0070492 ISO     oligosaccharide binding GO:0070492 ISS Biological Process     negative regulation of transcription by RNA polymerase II GO:0000122 ISO     negative regulation of transcription by RNA polymerase II GO:0000122 ISS     response to hypoxia GO:0001666 IDA     epithelial to mesenchymal transition GO:0001837 ISO     epithelial to mesenchymal transition GO:0001837 ISS     endothelial cell proliferation GO:0001935 ISO     endothelial cell proliferation GO:0001935 ISS     sprouting angiogenesis GO:0002040 IBA     sprouting angiogenesis GO:0002040 ISO     sprouting angiogenesis GO:0002040 ISS     positive regulation of epithelial to mesenchymal transition GO:0010718 ISO     positive regulation of epithelial to mesenchymal transition GO:0010718 ISS     peptidyl-lysine oxidation GO:0018057 ISO     peptidyl-lysine oxidation GO:0018057 ISS     collagen fibril organization GO:0030199 IBA     collagen fibril organization GO:0030199 ISO     collagen fibril organization GO:0030199 ISS     positive regulation of chondrocyte differentiation GO:0032332 IMP     protein modification process GO:0036211 ISO     protein modification process GO:0036211 ISS     endothelial cell migration GO:0043542 ISO     endothelial cell migration GO:0043542 ISS     negative regulation of DNA-templated transcription GO:0045892 ISO     negative regulation of DNA-templated transcription GO:0045892 ISS     response to copper ion GO:0046688 ISO     response to copper ion GO:0046688 ISS     heterochromatin organization GO:0070828 ISO     heterochromatin organization GO:0070828 ISS     negative regulation of stem cell population maintenance GO:1902455 IDA Subcellular Localization     chromatin GO:0000785 ISO     chromatin GO:0000785 ISS     basement membrane GO:0005604 ISO     basement membrane GO:0005604 ISS     extracellular space GO:0005615 HDA     extracellular space GO:0005615 IBA     extracellular space GO:0005615 ISO     extracellular space GO:0005615 ISS     nucleus GO:0005634 ISO     nucleus GO:0005634 ISS     nucleoplasm GO:0005654 IEA     nucleoplasm GO:0005654 ISO     endoplasmic reticulum GO:0005783 ISO     endoplasmic reticulum GO:0005783 ISS     membrane GO:0016020 IEA     collagen-containing extracellular matrix GO:0062023 HDA     collagen-containing extracellular matrix GO:0062023 IBA