Gene description for RGN
Gene name regucalcin
Gene symbol RGN
Other names/aliases GNL
HEL-S-41
RC
SMP30
Species Homo sapiens
 Database cross references - RGN
ExoCarta ExoCarta_9104
Entrez Gene 9104
HGNC 9989
MIM 300212
UniProt Q15493  
 RGN identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for RGN
Molecular Function
    zinc ion binding GO:0008270 IDA
    gluconolactonase activity GO:0004341 IDA
    enzyme regulator activity GO:0030234 IEA
    calcium ion binding GO:0005509 ISS
Biological Process
    regulation of calcium-mediated signaling GO:0050848 ISS
    L-ascorbic acid biosynthetic process GO:0019853 IEA
    cellular calcium ion homeostasis GO:0006874 ISS
    positive regulation of ATPase activity GO:0032781 ISS
Subcellular Localization
    nucleus GO:0005634 ISS
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 ISS
 Experiment description of studies that identified RGN in exosomes
1
Experiment ID 126
ISEV standards
EV Biophysical techniques
GAPDH
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for RGN
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which RGN is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here