Gene description for Pdia2
Gene name protein disulfide isomerase associated 2
Gene symbol Pdia2
Other names/aliases 1810041F13Rik
AI661267
Pdip
Pdipl
Species Mus musculus
 Database cross references - Pdia2
ExoCarta ExoCarta_69191
Vesiclepedia VP_69191
Entrez Gene 69191
UniProt D3Z6P0  
 Pdia2 identified in sEVs derived from the following tissue/cell type
Brain cancer cells 19109410    
 Gene ontology annotations for Pdia2
Molecular Function
    protein disulfide isomerase activity GO:0003756 IBA
    protein disulfide isomerase activity GO:0003756 TAS
    steroid binding GO:0005496 IEA
    protein-disulfide reductase activity GO:0015035 IEA
    protein-disulfide reductase activity GO:0015035 ISO
Biological Process
    protein folding GO:0006457 IBA
    response to endoplasmic reticulum stress GO:0034976 IBA
    platelet aggregation GO:0070527 IMP
Subcellular Localization
    endoplasmic reticulum GO:0005783 IBA
    endoplasmic reticulum lumen GO:0005788 IEA
 Experiment description of studies that identified Pdia2 in sEVs
1
Experiment ID 26
MISEV standards
EM
Biophysical techniques
Alix|GAPDH|HSP70|CD9
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 19109410    
Organism Mus musculus
Experiment description Proteomic and immunologic analyses of brain tumor exosomes.
Authors "Graner MW, Alzate O, Dechkovskaia AM, Keene JD, Sampson JH, Mitchell DA, Bigner DD"
Journal name FASEB
Publication year 2008
Sample Brain cancer cells
Sample name SMA560vIII
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.13-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
 Protein-protein interactions for Pdia2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Hspa5 14828
Co-purification Mus musculus
View the network image/svg+xml
 Pathways in which Pdia2 is involved
No pathways found





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