Gene description for Erp29
Gene name endoplasmic reticulum protein 29
Gene symbol Erp29
Other names/aliases 1200015M03Rik
2810446M09Rik
AW209030
Erp28
Erp31
PDI-Db
Species Mus musculus
 Database cross references - Erp29
ExoCarta ExoCarta_67397
Entrez Gene 67397
UniProt P57759  
 Erp29 identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Erp29
Molecular Function
    chaperone binding GO:0051087 ISO
    protein homodimerization activity GO:0042803 ISO
Biological Process
    positive regulation of gene expression GO:0010628 ISO
    regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway GO:1902235 IMP
    negative regulation of protein secretion GO:0050709 ISO
    ER to Golgi vesicle-mediated transport GO:0006888 NAS
    positive regulation of protein phosphorylation GO:0001934 ISO
    activation of MAPK activity GO:0000187 ISO
    protein secretion GO:0009306 IEA
    negative regulation of gene expression GO:0010629 ISO
Subcellular Localization
    endoplasmic reticulum GO:0005783 ISO
    cell GO:0005623 NAS
    membrane GO:0016020 ISO
    transport vesicle GO:0030133 ISO
    intracellular GO:0005622 NAS
    endoplasmic reticulum lumen GO:0005788 IEA
    extracellular exosome GO:0070062 ISO
    cytoplasm GO:0005737 NAS
    smooth endoplasmic reticulum GO:0005790 ISO
    cell surface GO:0009986 ISO
 Experiment description of studies that identified Erp29 in exosomes
1
Experiment ID 188
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH|UCHL1|HSP90
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Erp29
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Erp29 is involved
No pathways found





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