Gene description for Oxct1
Gene name 3-oxoacid CoA transferase 1
Gene symbol Oxct1
Other names/aliases 2610008O03Rik
Oxct
Oxct2a
Scot-s
Species Mus musculus
 Database cross references - Oxct1
ExoCarta ExoCarta_67041
Entrez Gene 67041
UniProt Q9D0K2  
 Oxct1 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Oxct1
Molecular Function
    transferase activity GO:0016740 IEA
    3-oxoacid CoA-transferase activity GO:0008260 ISO
    CoA-transferase activity GO:0008410 IEA
    protein homodimerization activity GO:0042803 ISO
Biological Process
    ketone catabolic process GO:0042182 IMP
    ketone body catabolic process GO:0046952 IMP
    cellular ketone body metabolic process GO:0046950 ISO
    metabolic process GO:0008152 IEA
    positive regulation of insulin secretion involved in cellular response to glucose stimulus GO:0035774 ISO
Subcellular Localization
    mitochondrion GO:0005739 ISO
 Experiment description of studies that identified Oxct1 in exosomes
1
Experiment ID 210
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD81|FLOT1
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Oxct1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Oxct1 is involved
PathwayEvidenceSource
Utilization of Ketone Bodies IEA Reactome





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