Gene description for Hspd1
Gene name	heat shock protein 1 (chaperonin)
Gene symbol	Hspd1
Other names/aliases	Hsp60 Hspd1-30p
Species	Rattus norvegicus
Database cross references - Hspd1
ExoCarta	ExoCarta_63868
Entrez Gene	63868
UniProt	P63039
Hspd1 identified in exosomes derived from the following tissue/cell type
Adipocytes	25998041
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Hspd1

Molecular Function     poly(A) RNA binding GO:0044822 ISO     lipopolysaccharide binding GO:0001530 ISO     misfolded protein binding GO:0051787 IPI     ATP binding GO:0005524 IEA     protein complex binding GO:0032403 IPI     protein heterodimerization activity GO:0046982 IPI     insulin binding GO:0043559 IPI     protease binding GO:0002020 IPI     p53 binding GO:0002039 ISO     protein binding GO:0005515 IPI     chaperone binding GO:0051087 ISO     ubiquitin protein ligase binding GO:0031625 ISO     double-stranded RNA binding GO:0003725 ISO Biological Process     'de novo' protein folding GO:0006458 IC     positive regulation of T cell mediated immune response to tumor cell GO:0002842 ISO     chaperone mediated protein folding requiring cofactor GO:0051085 IDA     positive regulation of interleukin-6 production GO:0032755 ISO     response to heat GO:0009408 IEP     protein stabilization GO:0050821 ISO     detection of misfolded protein GO:0002236 IDA     positive regulation of inflammatory response GO:0050729 IDA     positive regulation of interleukin-10 production GO:0032733 ISO     response to ATP GO:0033198 IEP     T cell activation GO:0042110 ISO     protein refolding GO:0042026 ISO     positive regulation of interleukin-12 production GO:0032735 ISO     response to unfolded protein GO:0006986 ISO     B cell activation GO:0042113 ISO     response to organic cyclic compound GO:0014070 IEP     response to lipopolysaccharide GO:0032496 IEP     positive regulation of interferon-gamma production GO:0032729 ISO     response to drug GO:0042493 IEP     MyD88-dependent toll-like receptor signaling pathway GO:0002755 ISO     negative regulation of apoptotic process GO:0043066 ISO     positive regulation of interferon-alpha production GO:0032727 ISO     response to organic substance GO:0010033 IEP     positive regulation of apoptotic process GO:0043065 ISO     negative regulation of neuron apoptotic process GO:0043524 IMP     positive regulation of T cell activation GO:0050870 ISO     B cell proliferation GO:0042100 ISO     response to hydrogen peroxide GO:0042542 IEP     activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 ISO     response to estrogen GO:0043627 IEP     positive regulation of macrophage activation GO:0043032 ISO     response to hypoxia GO:0001666 IEP     B cell cytokine production GO:0002368 ISO     response to cocaine GO:0042220 IEP     isotype switching to IgG isotypes GO:0048291 ISO Subcellular Localization     cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 ISO     zymogen granule GO:0042588 IDA     mitochondrial matrix GO:0005759 IEA     coated vesicle GO:0030135 ISO     extracellular exosome GO:0070062 ISO     secretory granule GO:0030141 ISO     cytosol GO:0005829 ISO     mitochondrial crista GO:0030061 IDA     myelin sheath GO:0043209 ISO     coated pit GO:0005905 ISO     cell surface GO:0009986 ISO     extracellular space GO:0005615 ISO     protein complex GO:0043234 ISS     rough endoplasmic reticulum GO:0005791 IDA     mitochondrial inner membrane GO:0005743 ISO     membrane raft GO:0045121 IDA     early endosome GO:0005769 ISO     plasma membrane GO:0005886 ISO     intracellular membrane-bounded organelle GO:0043231 ISO     Golgi apparatus GO:0005794 IDA     membrane GO:0016020 ISO     mitochondrion GO:0005739 ISO     cytoplasm GO:0005737 ISO     lipopolysaccharide receptor complex GO:0046696 ISO