Gene description for SEMA3G
Gene name sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
Gene symbol SEMA3G
Other names/aliases sem2
Species Homo sapiens
 Database cross references - SEMA3G
ExoCarta ExoCarta_56920
Vesiclepedia VP_56920
Entrez Gene 56920
HGNC 30400
UniProt Q9NS98  
 SEMA3G identified in sEVs derived from the following tissue/cell type
Saliva 19199708    
 Gene ontology annotations for SEMA3G
Molecular Function
    signaling receptor binding GO:0005102 ISS
    protein binding GO:0005515 IPI
    semaphorin receptor binding GO:0030215 IBA
    neuropilin binding GO:0038191 IBA
    chemorepellent activity GO:0045499 IBA
Biological Process
    neural crest cell migration GO:0001755 IBA
    axon guidance GO:0007411 IBA
    positive regulation of cell migration GO:0030335 IBA
    negative regulation of axon extension GO:0030517 ISS
    negative chemotaxis GO:0050919 IBA
    semaphorin-plexin signaling pathway GO:0071526 IBA
Subcellular Localization
    plasma membrane GO:0005886 IBA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified SEMA3G in sEVs
1
Experiment ID 66
MISEV standards
IEM
Biophysical techniques
TSG101|Alix|CD63|CD81
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for SEMA3G
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UFL1 23376
Affinity Capture-MS Homo sapiens
2 DDX58 23586
Affinity Capture-RNA Homo sapiens
3 RHOU 58480
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which SEMA3G is involved
No pathways found





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