TPPP3 
                                                                    Gene name 
                                                                    tubulin polymerization-promoting protein family member 3  
                                                                
                                                                    Gene symbol 
                                                                    TPPP3  
                                                                
                                                                    Other names/aliases 
                                                                    CGI-38 
                                                                 
                                                                                                                                
                                                                    Species 
                                                                    Homo sapiens 
                                                                 
                                                                
                                                                
                                                                    
                                                                    TPPP3 
                                                                        ExoCarta 
                                                                        ExoCarta_51673 
                                                                     
                                                                    
                                                                        Vesiclepedia 
                                                                        VP_51673  
                                                                    
                                                                        Entrez Gene 
                                                                        51673  
                                                                                                                                            
                                                                            HGNC 
                                                                            24162  
                                                                                                                                                                                                                                                                                    
                                                                            UniProt 
                                                                            
                                                                                
                                                                                                                                                                            
                                                                                        Q9BW30   
                                                                                    
                                                                             
                                                                         
                                                                    
                                                                    
                                                                    
                                                                    TPPP3  identified in sEVs derived from the following tissue/cell type
                                                                                
                                                                                    
                                                                                        Gastric cancer cells 
                                                                                 
                                                                                
                                                                                                                                                                            33991177
                                                                                                
                                                                             
                                                                                                                                                    
                                                                                
                                                                                    
                                                                                        Gastric cancer cells 
                                                                                 
                                                                                
                                                                                                                                                                            33991177
                                                                                                
                                                                             
                                                                                                                                                    
                                                                                
                                                                                    
                                                                                        Gastric cancer cells 
                                                                                 
                                                                                
                                                                                                                                                                            33991177
                                                                                                
                                                                             
                                                                                                                                                
                                                            
                                                            
                                                            
                                                                
                                                                    TPPP3 
                                                                        
                                                                            
                                                                                
                                                                         
                                                                     
                                                            
                                                            
                                                         
                                                        
                                                        
                                                            
                                                                TPPP3  in sEVs
                                                                                
                                                                                    
                                                                                        
                                                                                            1 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        363 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                DCLK1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            33991177
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Proteomics 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Gastric cancer cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        MKN1 - 100K pellet 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Western blotting 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            2 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        364 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                DCLK1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            33991177
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Proteomics 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Gastric cancer cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        MKN1 - 100K pellet 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Western blotting 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                            
                                                                            
                                                                                
                                                                                    
                                                                                        
                                                                                            3 
                                                                                            
                                                                                                
                                                                                                    
                                                                                                        Experiment ID 
                                                                                                        365 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    MISEV standards 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                                                                                                                                            ✘ 
                                                                                                                                                                                                                                             
                                                                                                                    Biophysical techniques 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Enriched markers 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                DCLK1
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    Negative markers 
                                                                                                                 
                                                                                                                
                                                                                                                    
                                                                                                                                                                                                                                                    ✔ 
                                                                                                                            
                                                                                                                                NTA
                                                                                                                            
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     
                                                                                                                 
                                                                                                            
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identified molecule 
                                                                                                        
                                                                                                            Protein
                                                                                                                                                                                                                                                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Identification method 
                                                                                                        
                                                                                                                                                                                                                            Mass spectrometry
                                                                                                                                                                                                                             
                                                                                                     
                                                                                                    
                                                                                                        PubMed ID 
                                                                                                        
                                                                                                                                                                                                                            33991177
                                                                                                                        
                                                                                                     
                                                                                                    
                                                                                                        Organism 
                                                                                                        Homo sapiens 
                                                                                                     
                                                                                                    
                                                                                                        Experiment description 
                                                                                                        Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells 
                                                                                                     
                                                                                                    
                                                                                                        Authors 
                                                                                                        "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M." 
                                                                                                     
                                                                                                    
                                                                                                        Journal name 
                                                                                                        
                                                                                                                                                                                                                            Proteomics 
                                                                                                                                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Publication year 
                                                                                                        2021 
                                                                                                     
                                                                                                    
                                                                                                        Sample 
                                                                                                        Gastric cancer cells 
                                                                                                     
                                                                                                    
                                                                                                        Sample name 
                                                                                                        MKN1 - 100K pellet 
                                                                                                     
                                                                                                    
                                                                                                    
                                                                                                        Isolation/purification methods 
                                                                                                        Differential centrifugation 
                                                                                                     
                                                                                                    
                                                                                                        Flotation density 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        -
                                                                                                                                                                                                                        
                                                                                                         
                                                                                                     
                                                                                                    
                                                                                                        Molecules identified in the study 
                                                                                                        Protein 
                                                                                                     
                                                                                                    
                                                                                                        Methods used in the study 
                                                                                                        Western blotting 
                                                                                                     
                                                                                                
                                                                                             
                                                                                         
                                                                                    
                                                                                 
                                                                             
                                                                                                                                
                                                         
                                                        
                                                        
                                                        
                                                            
                                                                
                                                                    
                                                                        
                                                                            TPPP3 
                                                                                
                                                                                    
                                                                                        
                                                                                              
                                                                                            Protein Interactor 
                                                                                            ExoCarta ID 
                                                                                            Identification method 
                                                                                            PubMed 
                                                                                            Species 
                                                                                         
                                                                                                                                                                                    
                                                                                                
                                                                                                    1 
                                                                                                                                                                                                                ARFGAP3 
                                                                                                            26286 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Co-fractionation 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    2 
                                                                                                                                                                                                                PPP2R2B 
                                                                                                            5521 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    3 
                                                                                                                                                                                                                SREBF2 
                                                                                                            6721 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Positive Genetic 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    4 
                                                                                                                                                                                                            ZC3HC1 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    5 
                                                                                                                                                                                                                GOT1 
                                                                                                            2805 
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Affinity Capture-MS 
                                                                                                                                    Homo sapiens 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                    
                                                                                                
                                                                                                    6 
                                                                                                                                                                                                            Htatsf1 
                                                                                                          
                                                                                                        
                                                                                                    
                                                                                                        
                                                                                                            
                                                                                                                                                                                                                                    
                                                                                                                                                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                                                                                                                                                                    Two-hybrid 
                                                                                                                                    Mus musculus 
                                                                                                                                                                                                                                                                 
                                                                                                                                                                                                                        
                                                                                                     
                                                                                             
                                                                                                                                                                                                                                                                                
                                                                                                    
                                                                                                        View the network 
                                                                                                     
                                                                                                    
                                                                                                        
                                                                                                                    
                                                                                                                    
                                                                                                                        
                                                                                                                        
                                                                                                                            
                                                                                                                            image/svg+xml 
                                                                                                                             
                                                                                                                         
                                                                                                                         
                                                                                                                         
                                                                                                         
                                                                                                     
                                                                                                 
                                                                                                                                                                            
                                                                                 
                                                                             
                                                            
                                                         
                                                        
                                                        
                                                        
                                                            
                                                                
                                                                    
                                                                        TPPP3  is involved
                                                                            
                                                                                                                                                                            No pathways found