Gene description for NKX6-1
Gene name	NK6 homeobox 1
Gene symbol	NKX6-1
Other names/aliases	NKX6.1 NKX6A
Species	Homo sapiens
Database cross references - NKX6-1
ExoCarta	ExoCarta_4825
Vesiclepedia	VP_4825
Entrez Gene	4825
HGNC	7839
MIM	602563
UniProt	P78426
NKX6-1 identified in sEVs derived from the following tissue/cell type
Urine	19056867

Gene ontology annotations for NKX6-1

Molecular Function     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA     DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IBA     DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 ISA     DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227 IEA     chromatin binding GO:0003682 IEA Biological Process     negative regulation of transcription by RNA polymerase II GO:0000122 ISS     pancreatic A cell differentiation GO:0003310 IEA     regulation of transcription by RNA polymerase II GO:0006357 IBA     transcription by RNA polymerase II GO:0006366 IEA     smoothened signaling pathway GO:0007224 IEA     response to xenobiotic stimulus GO:0009410 IEA     animal organ morphogenesis GO:0009887 TAS     glucose mediated signaling pathway GO:0010255 ISS     central nervous system neuron differentiation GO:0021953 IEA     cell differentiation GO:0030154 IBA     regulation of axon extension GO:0030516 IEA     pancreas development GO:0031016 ISS     positive regulation of insulin secretion GO:0032024 IEA     response to nicotine GO:0035094 IEA     type B pancreatic cell proliferation GO:0044342 ISS     positive regulation of neuron differentiation GO:0045666 IEA     positive regulation of transcription by RNA polymerase II GO:0045944 ISS     oligodendrocyte differentiation GO:0048709 IEA     positive regulation of oligodendrocyte differentiation GO:0048714 IEA     negative regulation of oligodendrocyte differentiation GO:0048715 IEA     positive regulation of DNA-binding transcription factor activity GO:0051091 ISS     cellular response to cytokine stimulus GO:0071345 IEA     cellular response to peptide hormone stimulus GO:0071375 IEA     type B pancreatic cell maturation GO:0072560 ISS     positive regulation of type B pancreatic cell development GO:2000078 ISS     regulation of neuron migration GO:2001222 IEA Subcellular Localization     chromatin GO:0000785 ISA     nucleus GO:0005634 IBA     extracellular exosome GO:0070062 HDA