Gene description for ATP1A4
Gene name	ATPase, Na+/K+ transporting, alpha 4 polypeptide
Gene symbol	ATP1A4
Other names/aliases	ATP1A1 ATP1AL2
Species	Homo sapiens
Database cross references - ATP1A4
ExoCarta	ExoCarta_480
Vesiclepedia	VP_480
Entrez Gene	480
HGNC	14073
MIM	607321
UniProt	Q13733
ATP1A4 identified in sEVs derived from the following tissue/cell type
Breast cancer cells	30918259
Breast cancer cells	30918259
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Neuroblastoma cells	25944692
Thymus	23844026

Gene ontology annotations for ATP1A4

Molecular Function     P-type sodium:potassium-exchanging transporter activity GO:0005391 IBA     P-type sodium:potassium-exchanging transporter activity GO:0005391 IGI     P-type sodium:potassium-exchanging transporter activity GO:0005391 ISS     P-type sodium:potassium-exchanging transporter activity GO:0005391 TAS     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     ATP hydrolysis activity GO:0016887 IEA     ATPase-coupled monoatomic cation transmembrane transporter activity GO:0019829 IGI     kinase binding GO:0019900 ISS     metal ion binding GO:0046872 IEA Biological Process     monoatomic ion transport GO:0006811 NAS     potassium ion transport GO:0006813 TAS     sodium ion transport GO:0006814 TAS     intracellular sodium ion homeostasis GO:0006883 IBA     cell surface receptor signaling pathway GO:0007166 ISS     spermatogenesis GO:0007283 IEA     fertilization GO:0009566 IEA     establishment or maintenance of transmembrane electrochemical gradient GO:0010248 IEA     intracellular potassium ion homeostasis GO:0030007 IBA     flagellated sperm motility GO:0030317 IDA     flagellated sperm motility GO:0030317 IMP     regulation of cellular pH GO:0030641 IDA     sodium ion transmembrane transport GO:0035725 IGI     sodium ion transmembrane transport GO:0035725 ISS     sodium ion export across plasma membrane GO:0036376 IBA     regulation of membrane potential GO:0042391 IEA     establishment of localization in cell GO:0051649 IEA     potassium ion transmembrane transport GO:0071805 IGI     potassium ion transmembrane transport GO:0071805 ISS     transport across blood-brain barrier GO:0150104 NAS     proton transmembrane transport GO:1902600 IBA     proton transmembrane transport GO:1902600 TAS     potassium ion import across plasma membrane GO:1990573 IBA Subcellular Localization     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 NAS     plasma membrane GO:0005886 TAS     sodium:potassium-exchanging ATPase complex GO:0005890 IBA     sodium:potassium-exchanging ATPase complex GO:0005890 IPI     sodium:potassium-exchanging ATPase complex GO:0005890 TAS     cell projection GO:0042995 IBA     membrane raft GO:0045121 ISS     sperm midpiece GO:0097225 IDA     photoreceptor cell cilium GO:0097733 IDA     rod photoreceptor outer segment GO:0120200 IDA