Gene description for Capn1
Gene name	calpain 1, (mu/I) large subunit
Gene symbol	Capn1
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Capn1
ExoCarta	ExoCarta_29153
Vesiclepedia	VP_29153
Entrez Gene	29153
UniProt	P97571
Capn1 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Capn1

Molecular Function     calcium-dependent cysteine-type endopeptidase activity GO:0004198 IBA     calcium-dependent cysteine-type endopeptidase activity GO:0004198 IDA     calcium-dependent cysteine-type endopeptidase activity GO:0004198 IEA     calcium-dependent cysteine-type endopeptidase activity GO:0004198 IMP     calcium-dependent cysteine-type endopeptidase activity GO:0004198 ISO     calcium ion binding GO:0005509 IEA     calcium ion binding GO:0005509 IMP     calcium ion binding GO:0005509 ISO     protein binding GO:0005515 IPI     cytoskeletal protein binding GO:0008092 IDA     peptidase activity GO:0008233 ISO     enzyme binding GO:0019899 IPI Biological Process     proteolysis GO:0006508 IBA     proteolysis GO:0006508 IDA     proteolysis GO:0006508 ISO     proteolysis GO:0006508 ISO     positive regulation of cardiac muscle cell apoptotic process GO:0010666 IMP     protein autoprocessing GO:0016540 IDA     protein catabolic process GO:0030163 IDA     protein catabolic process GO:0030163 IMP     negative regulation of actin filament polymerization GO:0030837 IMP     receptor catabolic process GO:0032801 IEA     receptor catabolic process GO:0032801 ISO     positive regulation of vascular permeability GO:0043117 IMP     response to arsenic-containing substance GO:0046685 IEP     regulation of catalytic activity GO:0050790 ISO     regulation of catalytic activity GO:0050790 ISS     mammary gland involution GO:0060056 IEA     mammary gland involution GO:0060056 ISO     cellular response to hydrogen peroxide GO:0070301 IMP     self proteolysis GO:0097264 IEA     self proteolysis GO:0097264 ISO     self proteolysis GO:0097264 ISS     protein catabolic process at postsynapse GO:0140249 EXP     protein catabolic process at postsynapse GO:0140249 IDA     protein catabolic process at postsynapse GO:0140249 IEP     protein catabolic process at postsynapse GO:0140249 IMP     negative regulation of non-canonical NF-kappaB signal transduction GO:1901223 IMP     positive regulation of leukocyte tethering or rolling GO:1903238 IMP     response to angiotensin GO:1990776 IMP Subcellular Localization     cornified envelope GO:0001533 IEA     cornified envelope GO:0001533 ISO     cytoplasm GO:0005737 IBA     cytoplasm GO:0005737 ISO     mitochondrion GO:0005739 IEA     mitochondrion GO:0005739 ISO     lysosome GO:0005764 IEA     lysosome GO:0005764 ISO     cytosol GO:0005829 IEA     cytosol GO:0005829 ISO     cytosol GO:0005829 ISS     plasma membrane GO:0005886 ISO     plasma membrane GO:0005886 ISS     postsynaptic density GO:0014069 IDA     membrane GO:0016020 ISO     presynapse GO:0098793 IDA     postsynapse GO:0098794 IDA     postsynapse GO:0098794 IMP     glutamatergic synapse GO:0098978 IDA     glutamatergic synapse GO:0098978 IMP