Gene description for MBD3L5
Gene name methyl-CpG binding domain protein 3-like 5
Gene symbol MBD3L5
Other names/aliases -
Species Homo sapiens
 Database cross references - MBD3L5
ExoCarta ExoCarta_284428
Vesiclepedia VP_284428
Entrez Gene 284428
HGNC 37204
UniProt A6NJ08  
 MBD3L5 identified in sEVs derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
 Gene ontology annotations for MBD3L5
Molecular Function
    methyl-CpG binding GO:0008327 IBA
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IBA
    DNA methylation-dependent constitutive heterochromatin formation GO:0006346 IBA
Subcellular Localization
    nucleus GO:0005634 IBA
 Experiment description of studies that identified MBD3L5 in sEVs
1
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MBD3L5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 KRAS 3845
Synthetic Lethality Homo sapiens
View the network image/svg+xml
 Pathways in which MBD3L5 is involved
No pathways found





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