| Experiment ID | 191 | 
                                                                                                                
                                                                                                                    | MISEV standards |  
                                                                                                                    | ✘ | Biophysical techniques |  
                                                                                                                    | ✔ 
                                                                                                                                Alix|CD81|CD9
                                                                                                                             | Enriched markers |  
                                                                                                                    | ✘ | Negative markers |  
                                                                                                                    | ✘ | Particle analysis |  | 
                                                                                                    
                                                                                                        | Identified molecule | protein   | 
                                                                                                    
                                                                                                        | Identification method | Mass spectrometry | 
                                                                                                    
                                                                                                        | PubMed ID | 20124223   | 
                                                                                                    
                                                                                                        | Organism | Homo sapiens | 
                                                                                                    
                                                                                                        | Experiment description | Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. | 
                                                                                                    
                                                                                                        | Authors | "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK." | 
                                                                                                    
                                                                                                        | Journal name | Mol Cell Proteomics | 
                                                                                                    
                                                                                                        | Publication year | 2010 | 
                                                                                                    
                                                                                                        | Sample | Squamous carcinoma cells | 
                                                                                                    
                                                                                                        | Sample name | Squamous carcinoma cell (A431) | 
                                                                                                    
                                                                                                    
                                                                                                        | Isolation/purification methods | Differential centrifugation | 
                                                                                                    
                                                                                                        | Flotation density | - | 
                                                                                                    
                                                                                                        | Molecules identified in the study | Protein | 
                                                                                                    
                                                                                                        | Methods used in the study | Mass spectrometry |