Gene description for Ugp2
Gene name UDP-glucose pyrophosphorylase 2
Gene symbol Ugp2
Other names/aliases UDPGP
UGPase
Species Mus musculus
 Database cross references - Ugp2
ExoCarta ExoCarta_216558
Entrez Gene 216558
UniProt Q91ZJ5  
 Ugp2 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Ugp2
Molecular Function
    UTP:glucose-1-phosphate uridylyltransferase activity GO:0003983 ISO
    glucose binding GO:0005536 ISO
    transferase activity GO:0016740 IEA
    pyrimidine ribonucleotide binding GO:0032557 ISO
    uridylyltransferase activity GO:0070569 IEA
    metal ion binding GO:0046872 IEA
    nucleotidyltransferase activity GO:0016779 IEA
    identical protein binding GO:0042802 ISO
Biological Process
    metabolic process GO:0008152 IEA
    UDP-glucose metabolic process GO:0006011 ISO
    glucose 1-phosphate metabolic process GO:0019255 ISO
Subcellular Localization
    nucleus GO:0005634 ISO
    extracellular exosome GO:0070062 ISO
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Ugp2 in exosomes
1
Experiment ID 210
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD81|FLOT1
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Ugp2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ugp2 is involved
PathwayEvidenceSource
Formation of the active cofactor, UDP-glucuronate IEA Reactome
Glycogen synthesis IEA Reactome





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