Gene description for Krt14
Gene name keratin 14
Gene symbol Krt14
Other names/aliases AI626930
K14
Krt-1.14
Krt1-14
Species Mus musculus
 Database cross references - Krt14
ExoCarta ExoCarta_16664
Entrez Gene 16664
UniProt Q61781  
 Krt14 identified in exosomes derived from the following tissue/cell type
Oligodendrocytes 21136642    
 Gene ontology annotations for Krt14
Molecular Function
    protein binding GO:0005515 IPI
    keratin filament binding GO:1990254 ISO
    structural molecule activity GO:0005198 IEA
Biological Process
    epithelial cell differentiation GO:0030855 ISO
    intermediate filament bundle assembly GO:0045110 ISO
    aging GO:0007568 ISO
    hair cycle GO:0042633 ISO
Subcellular Localization
    nucleus GO:0005634 ISO
    keratin filament GO:0045095 ISO
    extracellular exosome GO:0070062 ISO
    cytoplasm GO:0005737 ISO
    intracellular GO:0005622 IDA
    intermediate filament GO:0005882 ISO
    cell periphery GO:0071944 IDA
 Experiment description of studies that identified Krt14 in exosomes
1
Experiment ID 33
ISEV standards
✔
EM|IEM
EV Biophysical techniques
✔
Alix|TSG101
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21136642    
Organism Mus musculus
Experiment description Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?
Authors Kramer-Albers EM, Bretz N, Tenzer S, Winterstein C, Mobius W, Berger H, Nave KA, Schild H, Trotter J
Journal name PROTEOMICS_CL
Publication year 2007
Sample Oligodendrocytes
Sample name Oligodendrocytes
Oli-neu
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Krt14
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Krt14 is involved
PathwayEvidenceSource
Type I hemidesmosome assembly IEA Reactome





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