Gene description for Krt14
Gene name keratin 14
Gene symbol Krt14
Other names/aliases AI626930
K14
Krt-1.14
Krt1-14
Species Mus musculus
 Database cross references - Krt14
ExoCarta ExoCarta_16664
Vesiclepedia VP_16664
Entrez Gene 16664
UniProt Q61781  
 Krt14 identified in sEVs derived from the following tissue/cell type
Oligodendrocytes 21136642    
 Gene ontology annotations for Krt14
Molecular Function
    structural molecule activity GO:0005198 IEA
    protein binding GO:0005515 IPI
    keratin filament binding GO:1990254 IEA
    keratin filament binding GO:1990254 ISO
Biological Process
    response to radiation GO:0009314 IDA
    keratinocyte differentiation GO:0030216 IDA
    epithelial cell differentiation GO:0030855 IBA
    epithelial cell differentiation GO:0030855 ISO
    hair cycle GO:0042633 IEA
    hair cycle GO:0042633 ISO
    intermediate filament organization GO:0045109 IBA
    intermediate filament bundle assembly GO:0045110 ISO
    intermediate filament bundle assembly GO:0045110 ISS
    stem cell differentiation GO:0048863 IDA
Subcellular Localization
    cornified envelope GO:0001533 IDA
    intracellular anatomical structure GO:0005622 IDA
    nucleus GO:0005634 ISO
    nucleus GO:0005634 ISS
    cytoplasm GO:0005737 ISO
    cytoplasm GO:0005737 ISS
    cytoskeleton GO:0005856 IBA
    intermediate filament GO:0005882 ISO
    keratin filament GO:0045095 IBA
    keratin filament GO:0045095 IDA
    keratin filament GO:0045095 ISO
    basal part of cell GO:0045178 IDA
    cell periphery GO:0071944 IDA
 Experiment description of studies that identified Krt14 in sEVs
1
Experiment ID 33
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21136642    
Organism Mus musculus
Experiment description Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?
Authors "Kramer-Albers EM, Bretz N, Tenzer S, Winterstein C, Mobius W, Berger H, Nave KA, Schild H, Trotter J"
Journal name PROTEOMICS_CL
Publication year 2007
Sample Oligodendrocytes
Sample name Oligodendrocytes
Oli-neu
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Krt14
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Invs  
Affinity Capture-MS Mus musculus
2 Eps15 13858
Co-fractionation Mus musculus
3 Nphp4  
Affinity Capture-MS Mus musculus
4 Atxn1  
Proximity Label-MS Mus musculus
5 Kctd13  
Affinity Capture-MS Mus musculus
6 Thrb  
Affinity Capture-MS Mus musculus
7 Ahi1  
Affinity Capture-MS Mus musculus
8 Pkp1  
Co-fractionation Mus musculus
9 Mks1  
Affinity Capture-MS Mus musculus
10 Iqcb1  
Affinity Capture-MS Mus musculus
View the network image/svg+xml



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