Gene description for AEBP1
Gene name AE binding protein 1
Gene symbol AEBP1
Other names/aliases ACLP
Species Homo sapiens
 Database cross references - AEBP1
ExoCarta ExoCarta_165
Entrez Gene 165
HGNC 303
MIM 602981
UniProt Q8IUX7  
 AEBP1 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
Saliva 19199708    
 Gene ontology annotations for AEBP1
Molecular Function
    zinc ion binding GO:0008270 IEA
    carboxypeptidase activity GO:0004180 TAS
    transcription corepressor activity GO:0003714 IEA
    calmodulin binding GO:0005516 IEA
    RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription GO:0001227 IMP
    metallocarboxypeptidase activity GO:0004181 IEA
    RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977 IDA
    sequence-specific DNA binding transcription factor activity GO:0003700 TAS
Biological Process
    proteolysis GO:0006508 IEA
    negative regulation of transcription from RNA polymerase II promoter GO:0000122 IMP
    muscle organ development GO:0007517 TAS
    transcription, DNA-templated GO:0006351 IEA
    skeletal system development GO:0001501 TAS
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    nucleus GO:0005634 IEA
    extracellular space GO:0005615 IDA
    extracellular matrix GO:0031012 IDA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified AEBP1 in exosomes
1
Experiment ID 126
ISEV standards
EV Biophysical techniques
GAPDH
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
2
Experiment ID 66
ISEV standards
IEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
CD63|CD81
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for AEBP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TCF3  
Invitro Homo sapiens
View the network image/svg+xml
 Pathways in which AEBP1 is involved
No pathways found





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