Gene description for Hnrnpab
Gene name heterogeneous nuclear ribonucleoprotein A/B
Gene symbol Hnrnpab
Other names/aliases 3010025C11Rik
CBF-A
Cgbfa
Hnrpab
Species Mus musculus
 Database cross references - Hnrnpab
ExoCarta ExoCarta_15384
Entrez Gene 15384
UniProt Q99020  
 Hnrnpab identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
Pancreatic cells 19351151    
 Gene ontology annotations for Hnrnpab
Molecular Function
    RNA binding GO:0003723 IPI
    sequence-specific DNA binding GO:0043565 IDA
    nucleic acid binding GO:0003676 IEA
    nucleotide binding GO:0000166 IEA
    sequence-specific DNA binding transcription factor activity GO:0003700 IDA
    protein binding GO:0005515 IPI
    poly(A) RNA binding GO:0044822 ISO
    DNA binding GO:0003677 IEA
Biological Process
    regulation of transcription, DNA-templated GO:0006355 IEA
    positive regulation of transcription, DNA-templated GO:0045893 IDA
    negative regulation of transcription from RNA polymerase II promoter GO:0000122 IGI
    epithelial to mesenchymal transition GO:0001837 IDA
    transcription, DNA-templated GO:0006351 IEA
Subcellular Localization
    cytoplasm GO:0005737 IDA
    nucleoplasm GO:0005654 ISO
    ribonucleoprotein complex GO:0030529 ISO
    RNA polymerase II transcription factor complex GO:0090575 IDA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified Hnrnpab in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
2
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Hnrnpab
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Hnrnpab is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here