Gene description for Gng12
Gene name guanine nucleotide binding protein (G protein), gamma 12
Gene symbol Gng12
Other names/aliases 2010305F15Rik
AA536815
AI115529
AI314170
AI842738
Species Mus musculus
 Database cross references - Gng12
ExoCarta ExoCarta_14701
Entrez Gene 14701
UniProt Q9DAS9  
 Gng12 identified in exosomes derived from the following tissue/cell type
Oligodendrocytes 21136642    
 Gene ontology annotations for Gng12
Molecular Function
    PDZ domain binding GO:0030165 ISO
    phosphate ion binding GO:0042301 ISO
    signal transducer activity GO:0004871 IEA
Biological Process
    signal transduction GO:0007165 IEA
    G-protein coupled receptor signaling pathway GO:0007186 IEA
Subcellular Localization
    heterotrimeric G-protein complex GO:0005834 IEA
    extracellular exosome GO:0070062 ISO
    membrane GO:0016020 IEA
    plasma membrane GO:0005886 IEA
    actin filament GO:0005884 ISO
 Experiment description of studies that identified Gng12 in exosomes
1
Experiment ID 33
ISEV standards
✔
EM|IEM
EV Biophysical techniques
✔
Alix|TSG101
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21136642    
Organism Mus musculus
Experiment description Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?
Authors Kramer-Albers EM, Bretz N, Tenzer S, Winterstein C, Mobius W, Berger H, Nave KA, Schild H, Trotter J
Journal name PROTEOMICS_CL
Publication year 2007
Sample Oligodendrocytes
Sample name Oligodendrocytes
Oli-neu
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Gng12
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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