Gene description for ADGRG4
Gene name
adhesion G protein-coupled receptor G4
Gene symbol
ADGRG4
Other names/aliases
GPR112 PGR17 RP1-299I16
Species
Homo sapiens
Database cross references - ADGRG4
ExoCarta
ExoCarta_139378
Vesiclepedia
VP_139378
Entrez Gene
139378
HGNC
18992
UniProt
Q8IZF6
ADGRG4 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells
Unpublished / Not applicable
Squamous carcinoma cells
20124223
Gene ontology annotations for ADGRG4
Experiment description of studies that identified ADGRG4 in sEVs
1
Experiment ID
126
MISEV standards
✘
Biophysical techniques
✔
GAPDH
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry [LTQ-FT Ultra]
PubMed ID
Unpublished / Not applicable
Organism
Homo sapiens
Experiment description
Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors
"Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name
Mesenchymal Stem Cell Therapy
Publication year
2011
Sample
Mesenchymal stem cells
Sample name
huES9.E1
Isolation/purification methods
HPLC
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Antobody array Mass spectrometry
2
Experiment ID
191
MISEV standards
✘
Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
20124223
Organism
Homo sapiens
Experiment description
Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors
"Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name
Mol Cell Proteomics
Publication year
2010
Sample
Squamous carcinoma cells
Sample name
Squamous carcinoma cell (A431)
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for ADGRG4
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
CEP72
Affinity Capture-MS
Homo sapiens
2
TRIM21
6737
Affinity Capture-MS
Homo sapiens
3
PARK2
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which ADGRG4 is involved
No pathways found