Gene description for C1QTNF3
Gene name C1q and tumor necrosis factor related protein 3
Gene symbol C1QTNF3
Other names/aliases C1ATNF3
CORCS
CORS
CORS-26
CORS26
CTRP3
Species Homo sapiens
 Database cross references - C1QTNF3
ExoCarta ExoCarta_114899
Entrez Gene 114899
HGNC 14326
MIM 612045
UniProt Q9BXJ4  
 C1QTNF3 identified in exosomes derived from the following tissue/cell type
Saliva 19199708    
 Gene ontology annotations for C1QTNF3
Molecular Function
    molecular_function GO:0003674 ND
    protein binding GO:0005515 IPI
Biological Process
    cellular triglyceride homeostasis GO:0035356 IDA
    negative regulation of NF-kappaB import into nucleus GO:0042347 IDA
    negative regulation of gene expression GO:0010629 IDA
    positive regulation of adiponectin secretion GO:0070165 IDA
    protein trimerization GO:0070206 IDA
    negative regulation of interleukin-6 secretion GO:1900165 IDA
    positive regulation of cytokine secretion GO:0050715 IDA
    negative regulation of inflammatory response GO:0050728 IDA
    negative regulation of monocyte chemotactic protein-1 production GO:0071638 IDA
    negative regulation of gluconeogenesis GO:0045721 IDA
    fat cell differentiation GO:0045444 IEP
Subcellular Localization
    collagen trimer GO:0005581 IEA
    extracellular space GO:0005615 ISS
    extracellular exosome GO:0070062 IDA
    cell GO:0005623 IDA
    membrane GO:0016020 IDA
 Experiment description of studies that identified C1QTNF3 in exosomes
1
Experiment ID 66
ISEV standards
IEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
CD63|CD81
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for C1QTNF3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which C1QTNF3 is involved
No pathways found





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