Gene description for Actg2
Gene name actin, gamma 2, smooth muscle, enteric
Gene symbol Actg2
Other names/aliases ACTA3
Act-4
Act4
SMGA
Species Mus musculus
 Database cross references - Actg2
ExoCarta ExoCarta_11468
Vesiclepedia VP_11468
Entrez Gene 11468
UniProt P63268  
 Actg2 identified in sEVs derived from the following tissue/cell type
Mov neuroglial cells 15210972    
 Gene ontology annotations for Actg2
Molecular Function
    ATP binding GO:0005524 IEA
    hydrolase activity GO:0016787 IEA
Biological Process
    positive regulation of gene expression GO:0010628 ISS
    mesenchyme migration GO:0090131 ISS
Subcellular Localization
    cytoplasm GO:0005737 ISS
    cytoskeleton GO:0005856 IEA
    actin cytoskeleton GO:0015629 IBA
    lamellipodium GO:0030027 ISS
    filopodium GO:0030175 ISS
    myosin filament GO:0032982 ISS
    cell body GO:0044297 ISS
    cell periphery GO:0071944 IDA
 Experiment description of studies that identified Actg2 in sEVs
1
Experiment ID 39
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG101|HSC70|FLOT1
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15210972    
Organism Mus musculus
Experiment description Cells release prions in association with exosomes.
Authors "Fevrier B, Vilette D, Archer F, Loew D, Faigle W, Vidal M, Laude H, Raposo G"
Journal name PNAS
Publication year 2004
Sample Mov neuroglial cells
Sample name Mov neuroglial cell
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Actg2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Zbtb7b  
Affinity Capture-MS Mus musculus
2 Plec 18810
Reconstituted Complex Mus musculus
View the network image/svg+xml
 Pathways in which Actg2 is involved
PathwayEvidenceSource
Muscle contraction IEA Reactome
Smooth Muscle Contraction IEA Reactome





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