Gene description for Hsd17b10
Gene name	hydroxysteroid (17-beta) dehydrogenase 10
Gene symbol	Hsd17b10
Other names/aliases	Hadh2
Species	Rattus norvegicus
Database cross references - Hsd17b10
ExoCarta	ExoCarta_63864
Vesiclepedia	VP_63864
Entrez Gene	63864
UniProt	O70351
Hsd17b10 identified in sEVs derived from the following tissue/cell type
Adipocytes	25998041
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Hsd17b10

Molecular Function     tRNA binding GO:0000049 IEA     tRNA binding GO:0000049 ISO     tRNA binding GO:0000049 ISS     amyloid-beta binding GO:0001540 IDA     3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 IEA     3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 ISO     3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 ISS     estradiol 17-beta-dehydrogenase [NAD(P)+] activity GO:0004303 IBA     estradiol 17-beta-dehydrogenase [NAD(P)+] activity GO:0004303 IDA     steroid binding GO:0005496 IDA     cholate 7-alpha-dehydrogenase activity GO:0008709 IEA     cholate 7-alpha-dehydrogenase activity GO:0008709 ISO     cholate 7-alpha-dehydrogenase activity GO:0008709 ISS     oxidoreductase activity GO:0016491 IEA     acetoacetyl-CoA reductase activity GO:0018454 IDA     testosterone dehydrogenase [NAD(P)+] activity GO:0030283 ISO     testosterone dehydrogenase [NAD(P)+] activity GO:0030283 ISS     nuclear estrogen receptor binding GO:0030331 IPI     identical protein binding GO:0042802 IPI     17-beta-hydroxysteroid dehydrogenase (NAD+) activity GO:0044594 IEA     17-beta-hydroxysteroid dehydrogenase (NAD+) activity GO:0044594 ISO     17-beta-hydroxysteroid dehydrogenase (NAD+) activity GO:0044594 ISS     3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity GO:0047015 IEA     3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity GO:0047015 ISO     3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity GO:0047015 ISS     testosterone dehydrogenase (NAD+) activity GO:0047035 IEA     testosterone dehydrogenase (NAD+) activity GO:0047035 ISO     testosterone dehydrogenase (NAD+) activity GO:0047035 ISS     androstan-3-alpha,17-beta-diol dehydrogenase activity GO:0047044 IEA     NAD binding GO:0051287 IDA     chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity GO:0106281 IEA     chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity GO:0106281 ISO     chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity GO:0106281 ISS     isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity GO:0106282 IEA     isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity GO:0106282 ISO     isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity GO:0106282 ISS     ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity GO:0106283 IEA     ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity GO:0106283 ISO     ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity GO:0106283 ISS Biological Process     isoleucine catabolic process GO:0006550 IEA     isoleucine catabolic process GO:0006550 ISO     isoleucine catabolic process GO:0006550 ISS     fatty acid metabolic process GO:0006631 IBA     fatty acid beta-oxidation GO:0006635 IEA     fatty acid beta-oxidation GO:0006635 ISO     fatty acid beta-oxidation GO:0006635 ISS     bile acid biosynthetic process GO:0006699 IEA     bile acid biosynthetic process GO:0006699 ISO     bile acid biosynthetic process GO:0006699 ISS     mitochondrion organization GO:0007005 IEA     mitochondrion organization GO:0007005 ISO     C21-steroid hormone metabolic process GO:0008207 IEA     C21-steroid hormone metabolic process GO:0008207 ISO     C21-steroid hormone metabolic process GO:0008207 ISS     androgen metabolic process GO:0008209 IBA     androgen metabolic process GO:0008209 IEA     androgen metabolic process GO:0008209 ISO     androgen metabolic process GO:0008209 ISS     estrogen metabolic process GO:0008210 IBA     estrogen metabolic process GO:0008210 IEA     estrogen metabolic process GO:0008210 ISO     estrogen metabolic process GO:0008210 ISS     male gonad development GO:0008584 IEP     Leydig cell differentiation GO:0033327 IEP     protein homotetramerization GO:0051289 IEA     protein homotetramerization GO:0051289 ISO     brexanolone metabolic process GO:0062173 IEA     brexanolone metabolic process GO:0062173 ISO     brexanolone metabolic process GO:0062173 ISS     mitochondrial tRNA methylation GO:0070901 IEA     mitochondrial tRNA methylation GO:0070901 ISO     mitochondrial tRNA methylation GO:0070901 ISS     mitochondrial tRNA 5'-end processing GO:0097745 IEA     mitochondrial tRNA 5'-end processing GO:0097745 ISO     mitochondrial tRNA 5'-end processing GO:0097745 ISS     mitochondrial tRNA 3'-end processing GO:1990180 IEA     mitochondrial tRNA 3'-end processing GO:1990180 ISO     mitochondrial tRNA 3'-end processing GO:1990180 ISS Subcellular Localization     mitochondrion GO:0005739 IBA     mitochondrion GO:0005739 ISO     mitochondrion GO:0005739 ISS     endoplasmic reticulum GO:0005783 ISO     mitochondrial ribonuclease P complex GO:0030678 IEA     mitochondrial ribonuclease P complex GO:0030678 ISO     mitochondrial ribonuclease P complex GO:0030678 ISS     mitochondrial nucleoid GO:0042645 IEA     mitochondrial nucleoid GO:0042645 ISO     mitochondrial nucleoid GO:0042645 ISS     tRNA methyltransferase complex GO:0043527 IEA     tRNA methyltransferase complex GO:0043527 ISO