Gene description for Cav2
Gene name	caveolin 2
Gene symbol	Cav2
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Cav2
ExoCarta	ExoCarta_363425
Vesiclepedia	VP_363425
Entrez Gene	363425
UniProt	Q2IBC5
Cav2 identified in sEVs derived from the following tissue/cell type
Adipocytes	25998041

Gene ontology annotations for Cav2

Molecular Function     SNARE binding GO:0000149 IDA     protein binding GO:0005515 IPI     protein kinase binding GO:0019901 IBA     protein kinase binding GO:0019901 IEA     protein kinase binding GO:0019901 ISO     syntaxin binding GO:0019905 IDA     protein-macromolecule adaptor activity GO:0030674 IEA     protein-macromolecule adaptor activity GO:0030674 ISO     mitogen-activated protein kinase kinase kinase binding GO:0031435 IPI     D1 dopamine receptor binding GO:0031748 ISO     D1 dopamine receptor binding GO:0031748 ISS     protein homodimerization activity GO:0042803 IEA     protein homodimerization activity GO:0042803 ISO     protein heterodimerization activity GO:0046982 IEA     protein heterodimerization activity GO:0046982 ISO     phosphoprotein binding GO:0051219 IPI     molecular adaptor activity GO:0060090 IBA     molecular adaptor activity GO:0060090 ISO     scaffold protein binding GO:0097110 IEA     scaffold protein binding GO:0097110 ISO Biological Process     endothelial cell proliferation GO:0001935 IEA     endothelial cell proliferation GO:0001935 ISO     negative regulation of endothelial cell proliferation GO:0001937 IBA     negative regulation of endothelial cell proliferation GO:0001937 IEA     negative regulation of endothelial cell proliferation GO:0001937 IMP     negative regulation of endothelial cell proliferation GO:0001937 ISO     negative regulation of endothelial cell proliferation GO:0001937 ISS     positive regulation of endothelial cell proliferation GO:0001938 IEA     positive regulation of endothelial cell proliferation GO:0001938 ISO     vesicle fusion GO:0006906 IEA     vesicle fusion GO:0006906 ISO     vesicle fusion GO:0006906 ISS     mitochondrion organization GO:0007005 IEA     mitochondrion organization GO:0007005 ISO     mitochondrion organization GO:0007005 ISS     endoplasmic reticulum organization GO:0007029 IEA     endoplasmic reticulum organization GO:0007029 ISO     endoplasmic reticulum organization GO:0007029 ISS     regulation of mitotic nuclear division GO:0007088 IEA     regulation of mitotic nuclear division GO:0007088 ISO     transforming growth factor beta receptor signaling pathway GO:0007179 IEA     transforming growth factor beta receptor signaling pathway GO:0007179 ISO     chemical synaptic transmission GO:0007268 IDA     cell population proliferation GO:0008283 ISO     insulin receptor signaling pathway GO:0008286 IBA     insulin receptor signaling pathway GO:0008286 IDA     insulin receptor signaling pathway GO:0008286 IEA     insulin receptor signaling pathway GO:0008286 ISO     skeletal muscle cell proliferation GO:0014856 IEA     skeletal muscle cell proliferation GO:0014856 ISO     negative regulation of skeletal muscle cell proliferation GO:0014859 IEA     negative regulation of skeletal muscle cell proliferation GO:0014859 ISO     vesicle organization GO:0016050 ISO     receptor-mediated endocytosis of virus by host cell GO:0019065 IEA     receptor-mediated endocytosis of virus by host cell GO:0019065 ISO     viral release from host cell GO:0019076 IEA     viral release from host cell GO:0019076 ISO     cell differentiation GO:0030154 IBA     negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 IEA     negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 ISO     positive regulation of MAPK cascade GO:0043410 IDA     positive regulation of MAPK cascade GO:0043410 IEA     positive regulation of MAPK cascade GO:0043410 ISO     positive regulation of GTPase activity GO:0043547 ISO     positive regulation by host of viral process GO:0044794 IEA     positive regulation by host of viral process GO:0044794 ISO     vesicle docking GO:0048278 IEA     vesicle docking GO:0048278 ISO     vesicle docking GO:0048278 ISS     skeletal muscle fiber development GO:0048741 IEA     skeletal muscle fiber development GO:0048741 ISO     skeletal muscle fiber development GO:0048741 ISS     positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 IDA     regulation of cytosolic calcium ion concentration GO:0051480 IBA     positive regulation of dopamine receptor signaling pathway GO:0060161 IEA     positive regulation of dopamine receptor signaling pathway GO:0060161 ISO     positive regulation of dopamine receptor signaling pathway GO:0060161 ISS     caveola assembly GO:0070836 IBA     caveola assembly GO:0070836 IEA     caveola assembly GO:0070836 ISO     caveola assembly GO:0070836 ISS     basement membrane organization GO:0071711 IEA     basement membrane organization GO:0071711 ISO     positive regulation of protein localization to nucleus GO:1900182 IDA Subcellular Localization     Golgi membrane GO:0000139 IEA     acrosomal membrane GO:0002080 IEA     acrosomal membrane GO:0002080 ISO     caveolar macromolecular signaling complex GO:0002095 IEA     caveolar macromolecular signaling complex GO:0002095 ISO     nuclear envelope GO:0005635 IDA     nuclear inner membrane GO:0005637 IDA     Golgi apparatus GO:0005794 IBA     Golgi apparatus GO:0005794 IDA     lipid droplet GO:0005811 IDA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 ISO     caveola GO:0005901 IDA     caveola GO:0005901 ISO     caveola GO:0005901 ISS     focal adhesion GO:0005925 IBA     focal adhesion GO:0005925 IEA     focal adhesion GO:0005925 ISO     cell surface GO:0009986 IDA     membrane GO:0016020 ISO     transport vesicle GO:0030133 IEA     transport vesicle GO:0030133 ISO     cytoplasmic vesicle GO:0031410 IBA     cytoplasmic vesicle GO:0031410 ISO     protein-containing complex GO:0032991 IDA     protein-containing complex GO:0032991 ISO     sarcolemma GO:0042383 IBA     plasma membrane raft GO:0044853 ISO     plasma membrane raft GO:0044853 ISS     membrane raft GO:0045121 IDA     membrane raft GO:0045121 ISO     synapse GO:0045202 IEA     perinuclear region of cytoplasm GO:0048471 IBA     perinuclear region of cytoplasm GO:0048471 IEA     perinuclear region of cytoplasm GO:0048471 ISO     perinuclear region of cytoplasm GO:0048471 ISS