Gene description for Rras
Gene name related RAS viral (r-ras) oncogene homolog
Gene symbol Rras
Other names/aliases p23
Species Rattus norvegicus
 Database cross references - Rras
ExoCarta ExoCarta_361568
Vesiclepedia VP_361568
Entrez Gene 361568
UniProt D3Z8L7  
 Rras identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Rras
Molecular Function
    GTPase activity GO:0003924 IBA
    GTPase activity GO:0003924 ISO
    protein binding GO:0005515 IPI
    GTP binding GO:0005525 IBA
    GDP binding GO:0019003 IBA
    GDP binding GO:0019003 ISO
    protein-containing complex binding GO:0044877 ISO
Biological Process
    leukocyte differentiation GO:0002521 ISO
    signal transduction GO:0007165 IEA
    positive regulation of endothelial cell migration GO:0010595 ISO
    cell migration GO:0016477 ISO
    Schwann cell migration GO:0036135 ISO
    positive regulation of angiogenesis GO:0045766 ISO
    positive regulation of angiogenesis GO:0045766 ISS
    regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0051896 ISO
    face morphogenesis GO:0060325 ISO
    regulation of ERK1 and ERK2 cascade GO:0070372 ISO
    negative regulation of Schwann cell migration GO:1900148 ISO
    positive regulation of endothelial cell-matrix adhesion via fibronectin GO:1904906 ISO
    positive regulation of vasculogenesis GO:2001214 ISO
Subcellular Localization
    plasma membrane GO:0005886 IBA
 Experiment description of studies that identified Rras in sEVs
1
Experiment ID 225
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Rras
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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