Gene description for Atp1a3
Gene name	ATPase, Na+/K+ transporting, alpha 3 polypeptide
Gene symbol	Atp1a3
Other names/aliases	Atpa1a3
Species	Rattus norvegicus
Database cross references - Atp1a3
ExoCarta	ExoCarta_24213
Vesiclepedia	VP_24213
Entrez Gene	24213
UniProt	P06687
Atp1a3 identified in sEVs derived from the following tissue/cell type
Adipocytes	25998041

Gene ontology annotations for Atp1a3

Molecular Function     amyloid-beta binding GO:0001540 IDA     amyloid-beta binding GO:0001540 IEA     amyloid-beta binding GO:0001540 IPI     amyloid-beta binding GO:0001540 ISO     P-type sodium:potassium-exchanging transporter activity GO:0005391 IBA     P-type sodium:potassium-exchanging transporter activity GO:0005391 IEA     P-type sodium:potassium-exchanging transporter activity GO:0005391 ISO     P-type sodium:potassium-exchanging transporter activity GO:0005391 ISS     P-type sodium:potassium-exchanging transporter activity GO:0005391 NAS     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     P-type potassium transmembrane transporter activity GO:0008556 IEA     ATP hydrolysis activity GO:0016887 IEA     D1 dopamine receptor binding GO:0031748 IPI     heparan sulfate proteoglycan binding GO:0043395 ISO     metal ion binding GO:0046872 IEA     protein-folding chaperone binding GO:0051087 IEA     protein-folding chaperone binding GO:0051087 ISO     P-type sodium:potassium-exchanging transporter activity involved in regulation of cardiac muscle cell membrane potential GO:0086037 ISO Biological Process     potassium ion transport GO:0006813 IDA     sodium ion transport GO:0006814 IDA     intracellular sodium ion homeostasis GO:0006883 IBA     intracellular sodium ion homeostasis GO:0006883 IEA     intracellular sodium ion homeostasis GO:0006883 ISO     response to stress GO:0006950 ISO     gamma-aminobutyric acid signaling pathway GO:0007214 ISO     learning GO:0007612 ISO     memory GO:0007613 ISO     circadian rhythm GO:0007623 ISO     locomotory behavior GO:0007626 ISO     blood circulation GO:0008015 ISO     determination of adult lifespan GO:0008340 ISO     adult locomotory behavior GO:0008344 ISO     visual learning GO:0008542 ISO     response to temperature stimulus GO:0009266 ISO     response to xenobiotic stimulus GO:0009410 ISO     response to hormone GO:0009725 ISO     response to lithium ion GO:0010226 ISO     establishment or maintenance of transmembrane electrochemical gradient GO:0010248 IEA     response to activity GO:0014823 ISO     transmission of nerve impulse GO:0019226 ISO     calcium-mediated signaling GO:0019722 ISO     L-ascorbic acid metabolic process GO:0019852 ISO     thalamus development GO:0021794 ISO     cerebral cortex development GO:0021987 IEP     cerebral cortex development GO:0021987 ISO     neurogenesis GO:0022008 ISO     intracellular potassium ion homeostasis GO:0030007 IBA     intracellular potassium ion homeostasis GO:0030007 IEA     intracellular potassium ion homeostasis GO:0030007 ISO     sleep GO:0030431 ISO     brain-derived neurotrophic factor receptor signaling pathway GO:0031547 ISO     social behavior GO:0035176 ISO     ionotropic glutamate receptor signaling pathway GO:0035235 ISO     multicellular organism growth GO:0035264 ISO     response to potassium ion GO:0035864 ISO     response to immobilization stress GO:0035902 ISO     sodium ion export across plasma membrane GO:0036376 IBA     sodium ion export across plasma membrane GO:0036376 IEA     sodium ion export across plasma membrane GO:0036376 ISO     locomotion GO:0040011 ISO     fear response GO:0042596 ISO     phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0043491 ISO     pore complex assembly GO:0046931 ISO     carboxylic acid transport GO:0046942 ISO     habituation GO:0046959 ISO     regulation of short-term neuronal synaptic plasticity GO:0048172 ISO     neuromuscular process controlling balance GO:0050885 ISO     cognition GO:0050890 ISO     neuromuscular process GO:0050905 ISO     response to electrical stimulus GO:0051602 ISO     membrane depolarization GO:0051899 ISO     cardiac muscle contraction GO:0060048 ISO     motor behavior GO:0061744 ISO     ERK1 and ERK2 cascade GO:0070371 ISO     cellular response to retinoic acid GO:0071300 IEP     potassium ion transmembrane transport GO:0071805 IEA     response to monoamine GO:0071867 ISO     regulation of cardiac muscle cell membrane potential GO:0086036 ISO     response to environmental enrichment GO:0090648 ISO     walking behavior GO:0090659 ISO     cellular response to thyroid hormone stimulus GO:0097067 IEP     proton transmembrane transport GO:1902600 IBA     response to methamphetamine hydrochloride GO:1904313 ISO     cellular response to amyloid-beta GO:1904646 IDA     neuron projection maintenance GO:1990535 IEA     neuron projection maintenance GO:1990535 ISO     potassium ion import across plasma membrane GO:1990573 IBA     potassium ion import across plasma membrane GO:1990573 IEA     potassium ion import across plasma membrane GO:1990573 ISO Subcellular Localization     photoreceptor inner segment GO:0001917 ISO     nucleus GO:0005634 ISO     cytoplasm GO:0005737 ISO     endoplasmic reticulum GO:0005783 IEA     endoplasmic reticulum GO:0005783 ISO     endoplasmic reticulum GO:0005783 ISS     Golgi apparatus GO:0005794 IEA     Golgi apparatus GO:0005794 ISO     Golgi apparatus GO:0005794 ISS     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IEA     plasma membrane GO:0005886 ISO     plasma membrane GO:0005886 ISO     plasma membrane GO:0005886 ISS     sodium:potassium-exchanging ATPase complex GO:0005890 IDA     sodium:potassium-exchanging ATPase complex GO:0005890 IEA     sodium:potassium-exchanging ATPase complex GO:0005890 ISO     sodium:potassium-exchanging ATPase complex GO:0005890 NAS     cell surface GO:0009986 ISO     endomembrane system GO:0012505 IEA     membrane GO:0016020 IDA     axon GO:0030424 IDA     axon GO:0030424 IEA     axon GO:0030424 ISO     organelle membrane GO:0031090 IEA     organelle membrane GO:0031090 ISO     protein-containing complex GO:0032991 ISO     sarcolemma GO:0042383 ISO     presynaptic membrane GO:0042734 IDA     neuronal cell body GO:0043025 IEA     neuronal cell body GO:0043025 ISO     myelin sheath GO:0043209 IDA     calyx of Held GO:0044305 IDA     dendritic spine neck GO:0044326 IDA     dendritic spine head GO:0044327 IDA     synapse GO:0045202 IDA     postsynapse GO:0098794 IDA     neuron to neuron synapse GO:0098984 ISO