Gene description for Rab1b
Gene name RAB1B, member RAS oncogene family
Gene symbol Rab1b
Other names/aliases Rab1bl
Species Rattus norvegicus
 Database cross references - Rab1b
ExoCarta ExoCarta_100126191
Vesiclepedia VP_100126191
Entrez Gene 100126191
 Rab1b identified in sEVs derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Rab1b
Molecular Function
    GTPase activity GO:0003924 IBA
    GTPase activity GO:0003924 IEA
    G protein activity GO:0003925 IEA
    GTP binding GO:0005525 IEA
    GTP binding GO:0005525 ISO
    GTP binding GO:0005525 ISS
Biological Process
    autophagosome assembly GO:0000045 IBA
    intracellular protein transport GO:0006886 IBA
    endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888 ISO
    Golgi organization GO:0007030 ISO
    Golgi organization GO:0007030 ISS
    protein transport GO:0015031 IEA
    establishment of endothelial intestinal barrier GO:0090557 ISO
    positive regulation of glycoprotein metabolic process GO:1903020 ISO
    regulation of autophagosome assembly GO:2000785 ISO
Subcellular Localization
    cytoplasm GO:0005737 IEA
    endoplasmic reticulum-Golgi intermediate compartment GO:0005793 ISO
    Golgi apparatus GO:0005794 ISO
    endomembrane system GO:0012505 IBA
    membrane GO:0016020 IEA
    phagophore assembly site membrane GO:0034045 ISO
    synapse GO:0045202 EXP
    synapse GO:0045202 IDA
    perinuclear region of cytoplasm GO:0048471 IEA
 Experiment description of studies that identified Rab1b in sEVs
1
Experiment ID 35
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|CD81|CD63
Enriched markers
✔
HSPA5
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Rab1b
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Fbxo21  
Affinity Capture-MS Rattus norvegicus
2 Itm2b 290364
Affinity Capture-MS Rattus norvegicus
View the network image/svg+xml
 Pathways in which Rab1b is involved
No pathways found





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