Gene description for Gnb2l1
Gene name	guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1
Gene symbol	Gnb2l1
Other names/aliases	RACK1
Species	Rattus norvegicus
Database cross references - Gnb2l1
ExoCarta	ExoCarta_83427
Vesiclepedia	VP_83427
Entrez Gene	83427
UniProt	P63245
Gnb2l1 identified in sEVs derived from the following tissue/cell type
Adipocytes	25998041
Hepatocytes	19367702
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Gnb2l1

Molecular Function     protein kinase C binding GO:0005080 IBA     protein kinase C binding GO:0005080 IC     protein kinase C binding GO:0005080 IDA     protein kinase C binding GO:0005080 ISO     protein binding GO:0005515 IPI     enzyme activator activity GO:0008047 ISO     ion channel inhibitor activity GO:0008200 IEA     ion channel inhibitor activity GO:0008200 ISO     cysteine-type endopeptidase activator activity involved in apoptotic process GO:0008656 ISO     enzyme binding GO:0019899 ISO     protein phosphatase binding GO:0019903 ISO     protein tyrosine kinase inhibitor activity GO:0030292 ISO     protein tyrosine kinase inhibitor activity GO:0030292 ISS     cyclin binding GO:0030332 ISO     receptor tyrosine kinase binding GO:0030971 ISO     receptor tyrosine kinase binding GO:0030971 ISS     signaling adaptor activity GO:0035591 ISO     SH2 domain binding GO:0042169 ISO     SH2 domain binding GO:0042169 ISS     identical protein binding GO:0042802 ISO     protein homodimerization activity GO:0042803 ISO     ribosome binding GO:0043022 IBA     ribosome binding GO:0043022 IEA     ribosome binding GO:0043022 ISO     ribosome binding GO:0043022 ISS     translation regulator activity GO:0045182 IEA     BH3 domain binding GO:0051434 ISO Biological Process     osteoblast differentiation GO:0001649 HDA     positive regulation of protein phosphorylation GO:0001934 ISO     positive regulation of protein phosphorylation GO:0001934 ISS     translation GO:0006412 IEA     translation GO:0006412 ISO     regulation of translation GO:0006417 IEA     apoptotic process GO:0006915 IEA     phospholipase C-activating G protein-coupled receptor signaling pathway GO:0007200 TAS     gastrulation GO:0007369 IEA     negative regulation of gene expression GO:0010629 ISO     protein ubiquitination GO:0016567 ISO     protein ubiquitination GO:0016567 ISS     negative regulation of translation GO:0017148 IMP     negative regulation of Wnt signaling pathway GO:0030178 ISS     negative regulation of cell growth GO:0030308 ISO     negative regulation of cell growth GO:0030308 ISS     positive regulation of cell migration GO:0030335 ISO     positive regulation of cell migration GO:0030335 ISS     positive regulation of protein-containing complex assembly GO:0031334 ISO     positive regulation of protein-containing complex assembly GO:0031334 ISS     positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436 ISO     positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436 ISS     regulation of protein localization GO:0032880 ISS     negative regulation of peptidyl-serine phosphorylation GO:0033137 ISO     positive regulation of Golgi to plasma membrane protein transport GO:0042998 ISO     positive regulation of Golgi to plasma membrane protein transport GO:0042998 ISS     positive regulation of apoptotic process GO:0043065 ISO     positive regulation of apoptotic process GO:0043065 ISS     pigmentation GO:0043473 IEA     pigmentation GO:0043473 ISO     positive regulation of GTPase activity GO:0043547 ISO     positive regulation of GTPase activity GO:0043547 ISS     negative regulation of smoothened signaling pathway GO:0045879 ISO     rhythmic process GO:0048511 IEA     negative regulation of phagocytosis GO:0050765 ISO     negative regulation of phagocytosis GO:0050765 ISS     regulation of cell division GO:0051302 ISS     regulation of cell cycle GO:0051726 ISO     regulation of cell cycle GO:0051726 ISS     negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0051898 ISO     positive regulation of mitochondrial depolarization GO:0051901 ISO     cellular response to glucose stimulus GO:0071333 ISO     cellular response to growth factor stimulus GO:0071363 ISO     cellular response to growth factor stimulus GO:0071363 ISS     rescue of stalled ribosome GO:0072344 IBA     rescue of stalled ribosome GO:0072344 ISO     rescue of stalled ribosome GO:0072344 ISS     regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0106070 ISO     regulation of protein localization to plasma membrane GO:1903076 IMP     negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide GO:1903751 IEA     negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide GO:1903751 ISO     regulation of establishment of cell polarity GO:2000114 ISS     positive regulation of gastrulation GO:2000543 ISS     positive regulation of cysteine-type endopeptidase activity GO:2001056 ISO     negative regulation of translational frameshifting GO:2001125 IBA     positive regulation of intrinsic apoptotic signaling pathway GO:2001244 ISO Subcellular Localization     phagocytic cup GO:0001891 ISO     phagocytic cup GO:0001891 ISS     nucleus GO:0005634 IBA     nucleus GO:0005634 ISO     nucleus GO:0005634 ISS     nucleoplasm GO:0005654 ISO     cytoplasm GO:0005737 IEA     cytoplasm GO:0005737 ISO     cytoplasm GO:0005737 ISS     mitochondrion GO:0005739 ISO     cytosol GO:0005829 IBA     cytosol GO:0005829 ISO     small ribosomal subunit GO:0015935 IDA     small ribosomal subunit GO:0015935 IEA     small ribosomal subunit GO:0015935 ISO     membrane GO:0016020 HDA     dendrite GO:0030425 IEA     dendrite GO:0030425 ISO     midbody GO:0030496 ISO     midbody GO:0030496 ISS     neuron projection GO:0043005 ISO     neuronal cell body GO:0043025 IEA     neuronal cell body GO:0043025 ISO     neuronal cell body GO:0043025 ISS     perikaryon GO:0043204 IEA     cell body GO:0044297 ISO     perinuclear region of cytoplasm GO:0048471 ISO     perinuclear region of cytoplasm GO:0048471 ISS     IRE1-RACK1-PP2A complex GO:1990630 ISO