Gene description for Gnaq
Gene name	guanine nucleotide binding protein (G protein), q polypeptide
Gene symbol	Gnaq
Other names/aliases	Galphaq
Species	Rattus norvegicus
Database cross references - Gnaq
ExoCarta	ExoCarta_81666
Vesiclepedia	VP_81666
Entrez Gene	81666
UniProt	P82471
Gnaq identified in sEVs derived from the following tissue/cell type
Adipocytes	25998041
Reticulocytes	21828046
Urine	20535238

Gene ontology annotations for Gnaq

Molecular Function     G protein-coupled receptor binding GO:0001664 IBA     G protein-coupled receptor binding GO:0001664 IEA     GTPase activity GO:0003924 IBA     GTPase activity GO:0003924 IEA     G protein activity GO:0003925 IEA     G protein activity GO:0003925 ISO     GTPase activator activity GO:0005096 IBA     GTPase activator activity GO:0005096 ISO     protein binding GO:0005515 IPI     GTP binding GO:0005525 IEA     enzyme regulator activity GO:0030234 IEA     enzyme regulator activity GO:0030234 ISO     G-protein beta/gamma-subunit complex binding GO:0031683 IBA     G-protein beta/gamma-subunit complex binding GO:0031683 IEA     protein-containing complex binding GO:0044877 IPI     metal ion binding GO:0046872 IEA     alkylglycerophosphoethanolamine phosphodiesterase activity GO:0047391 IDA Biological Process     skeletal system development GO:0001501 IEA     skeletal system development GO:0001501 ISO     action potential GO:0001508 IEA     action potential GO:0001508 ISO     negative regulation of protein kinase activity GO:0006469 ISO     G protein-coupled receptor signaling pathway GO:0007186 IEA     G protein-coupled receptor signaling pathway GO:0007186 ISO     adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0007189 IBA     adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0007189 IEA     adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0007189 ISO     phospholipase C-activating G protein-coupled receptor signaling pathway GO:0007200 IMP     phospholipase C-activating G protein-coupled receptor signaling pathway GO:0007200 ISO     phospholipase C-activating G protein-coupled glutamate receptor signaling pathway GO:0007206 ISO     phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway GO:0007207 IEA     phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway GO:0007207 ISO     phospholipase C-activating serotonin receptor signaling pathway GO:0007208 ISO     glutamate receptor signaling pathway GO:0007215 IBA     glutamate receptor signaling pathway GO:0007215 IEA     glutamate receptor signaling pathway GO:0007215 ISO     neuropeptide signaling pathway GO:0007218 ISO     heart development GO:0007507 IEA     heart development GO:0007507 ISO     regulation of blood pressure GO:0008217 IEA     regulation of blood pressure GO:0008217 ISO     post-embryonic development GO:0009791 IEA     post-embryonic development GO:0009791 ISO     regulation of platelet activation GO:0010543 IEA     regulation of platelet activation GO:0010543 ISO     regulation of platelet activation GO:0010543 ISS     neuron remodeling GO:0016322 IEA     neuron remodeling GO:0016322 ISO     forebrain neuron development GO:0021884 IEA     forebrain neuron development GO:0021884 ISO     positive regulation of insulin secretion GO:0032024 IEA     positive regulation of insulin secretion GO:0032024 ISO     response to prostaglandin E GO:0034695 ISO     maternal behavior GO:0042711 IEA     maternal behavior GO:0042711 ISO     embryonic digit morphogenesis GO:0042733 IEA     embryonic digit morphogenesis GO:0042733 ISO     negative regulation of apoptotic process GO:0043066 IMP     negative regulation of potassium ion transport GO:0043267 IMP     regulation of melanocyte differentiation GO:0045634 IEA     regulation of melanocyte differentiation GO:0045634 ISO     developmental pigmentation GO:0048066 IEA     developmental pigmentation GO:0048066 ISO     protein stabilization GO:0050821 ISO     phospholipase C-activating dopamine receptor signaling pathway GO:0060158 IEA     phospholipase C-activating dopamine receptor signaling pathway GO:0060158 ISO     regulation of canonical Wnt signaling pathway GO:0060828 ISO     endothelin receptor signaling pathway GO:0086100 IEA     endothelin receptor signaling pathway GO:0086100 ISO     ion channel modulating, G protein-coupled receptor signaling pathway GO:0099105 IEA     ion channel modulating, G protein-coupled receptor signaling pathway GO:0099105 ISO     cranial skeletal system development GO:1904888 IEA     cranial skeletal system development GO:1904888 ISO     ligand-gated ion channel signaling pathway GO:1990806 IEA     ligand-gated ion channel signaling pathway GO:1990806 ISO Subcellular Localization     cytoplasm GO:0005737 IBA     Golgi apparatus GO:0005794 IEA     heterotrimeric G-protein complex GO:0005834 IBA     heterotrimeric G-protein complex GO:0005834 IDA     heterotrimeric G-protein complex GO:0005834 IEA     plasma membrane GO:0005886 ISO     caveola GO:0005901 IDA     membrane GO:0016020 ISO     dendrite GO:0030425 IEA     dendrite GO:0030425 ISO     nuclear membrane GO:0031965 IEA     cell body GO:0044297 IEA     cell body GO:0044297 ISO     synapse GO:0045202 IEA     presynapse GO:0098793 IDA     presynapse GO:0098793 NAS     postsynaptic cytosol GO:0099524 ISO