Gene description for TUBB
Gene name tubulin, beta class I
Gene symbol TUBB
Other names/aliases TUBB2A
TUBB2B
TUBB5
Species Bos taurus
 Database cross references - TUBB
ExoCarta ExoCarta_615087
Vesiclepedia VP_615087
Entrez Gene 615087
UniProt Q2KJD0  
 TUBB identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for TUBB
Molecular Function
    GTPase activity GO:0003924 IEA
    structural constituent of cytoskeleton GO:0005200 IEA
    GTP binding GO:0005525 IEA
Biological Process
    microtubule cytoskeleton organization GO:0000226 IEA
    mitotic cell cycle GO:0000278 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    microtubule GO:0005874 IEA
 Experiment description of studies that identified TUBB in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TUBB
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DPYSL5  
Affinity Capture-Western Homo sapiens
2 DPYSL3 1809
Affinity Capture-Western Homo sapiens
3 CRMP1 1400
Affinity Capture-Western Homo sapiens
4 DPYSL4 10570
Affinity Capture-Western Homo sapiens
5 DPYSL2 1808
Affinity Capture-Western Homo sapiens
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