Gene description for IGF2R
Gene name insulin-like growth factor 2 receptor
Gene symbol IGF2R
Other names/aliases CI-MPR
CIMPR
Species Bos taurus
 Database cross references - IGF2R
ExoCarta ExoCarta_281849
Vesiclepedia VP_281849
Entrez Gene 281849
UniProt P08169  
 IGF2R identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for IGF2R
Molecular Function
    insulin-like growth factor binding GO:0005520 IEA
    D-mannose binding GO:0005537 IEA
    signaling receptor activity GO:0038023 IEA
Biological Process
    lysosomal transport GO:0007041 IEA
Subcellular Localization
    late endosome GO:0005770 IEA
    trans-Golgi network GO:0005802 IEA
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified IGF2R in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for IGF2R
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GGA3  
Reconstituted Complex Bos taurus
2 AP1G1  
Affinity Capture-Western Bos taurus
3 GGA1  
Reconstituted Complex Bos taurus
4 GGA2  
Reconstituted Complex Bos taurus
5 GGA1 26088
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which IGF2R is involved
No pathways found





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