Gene description for Pc
Gene name	pyruvate carboxylase
Gene symbol	Pc
Other names/aliases	Pcx
Species	Rattus norvegicus
Database cross references - Pc
ExoCarta	ExoCarta_25104
Vesiclepedia	VP_25104
Entrez Gene	25104
UniProt	P52873
Pc identified in sEVs derived from the following tissue/cell type
Adipocytes	25998041
Hepatocytes	19367702
Reticulocytes	21828046

Gene ontology annotations for Pc

Molecular Function     pyruvate carboxylase activity GO:0004736 IBA     pyruvate carboxylase activity GO:0004736 IDA     pyruvate carboxylase activity GO:0004736 IEA     pyruvate carboxylase activity GO:0004736 IMP     pyruvate carboxylase activity GO:0004736 ISO     ATP binding GO:0005524 IDA     ATP binding GO:0005524 IEA     biotin binding GO:0009374 IDA     biotin binding GO:0009374 IMP     carboxylic acid binding GO:0031406 IDA     identical protein binding GO:0042802 IEA     identical protein binding GO:0042802 ISO     metal ion binding GO:0046872 IEA Biological Process     pyruvate metabolic process GO:0006090 IBA     pyruvate metabolic process GO:0006090 IDA     pyruvate metabolic process GO:0006090 IEA     gluconeogenesis GO:0006094 IBA     gluconeogenesis GO:0006094 IDA     gluconeogenesis GO:0006094 IEA     gluconeogenesis GO:0006094 ISO     oxaloacetate metabolic process GO:0006107 IDA     lipid metabolic process GO:0006629 IEA     NADH metabolic process GO:0006734 IEA     NADH metabolic process GO:0006734 ISO     NADP metabolic process GO:0006739 IEA     NADP metabolic process GO:0006739 ISO     negative regulation of gene expression GO:0010629 IEA     negative regulation of gene expression GO:0010629 ISO     viral RNA genome packaging GO:0019074 IEA     viral RNA genome packaging GO:0019074 ISO     viral release from host cell GO:0019076 IEA     viral release from host cell GO:0019076 ISO     positive regulation by host of viral process GO:0044794 IEA     positive regulation by host of viral process GO:0044794 ISO     positive regulation of phospholipid biosynthetic process GO:0071073 IMP Subcellular Localization     cytoplasm GO:0005737 IBA     cytoplasm GO:0005737 ISO     mitochondrion GO:0005739 IEA     mitochondrion GO:0005739 ISO     mitochondrial matrix GO:0005759 ISO