Gene description for Glud1
Gene name glutamate dehydrogenase 1
Gene symbol Glud1
Other names/aliases Ac2-281
Gdh1
Glud
Gludeha
MRG-2
Species Rattus norvegicus
 Database cross references - Glud1
ExoCarta ExoCarta_24399
Vesiclepedia VP_24399
Entrez Gene 24399
UniProt P10860  
 Glud1 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Glud1
Molecular Function
    glutamate dehydrogenase (NAD+) activity GO:0004352 IBA
    glutamate dehydrogenase (NAD+) activity GO:0004352 IDA
    glutamate dehydrogenase (NAD+) activity GO:0004352 ISO
    glutamate dehydrogenase [NAD(P)+] activity GO:0004353 ISO
    glutamate dehydrogenase [NAD(P)+] activity GO:0004353 ISS
    glutamate dehydrogenase (NADP+) activity GO:0004354 IEA
    ATP binding GO:0005524 IEA
    GTP binding GO:0005525 ISO
    oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor GO:0016639 IEA
    enzyme binding GO:0019899 IPI
    protein homodimerization activity GO:0042803 ISO
    ADP binding GO:0043531 ISO
    NAD+ binding GO:0070403 ISO
    L-leucine binding GO:0070728 ISO
Biological Process
    amino acid metabolic process GO:0006520 IEA
    glutamate biosynthetic process GO:0006537 ISO
    glutamate catabolic process GO:0006538 IBA
    glutamate catabolic process GO:0006538 ISO
    glutamine metabolic process GO:0006541 ISO
    glutamine metabolic process GO:0006541 ISS
    long-term memory GO:0007616 IEP
    response to aluminum ion GO:0010044 IDA
    cerebellum development GO:0021549 IEP
    substantia nigra development GO:0021762 ISO
    positive regulation of insulin secretion GO:0032024 ISO
    positive regulation of insulin secretion GO:0032024 ISO
    tricarboxylic acid metabolic process GO:0072350 ISO
    tricarboxylic acid metabolic process GO:0072350 ISS
Subcellular Localization
    cytoplasm GO:0005737 ISO
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 ISO
    mitochondrial matrix GO:0005759 ISO
    endoplasmic reticulum GO:0005783 ISO
    endoplasmic reticulum GO:0005783 ISS
 Experiment description of studies that identified Glud1 in sEVs
1
Experiment ID 225
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Glud1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DYNLL1 8655
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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