Gene description for Ptgs1
Gene name	prostaglandin-endoperoxide synthase 1
Gene symbol	Ptgs1
Other names/aliases	COX1 Cox-1 Cox-3 PGHS-1 PHS 1 Pghs1
Species	Mus musculus
Database cross references - Ptgs1
ExoCarta	ExoCarta_19224
Vesiclepedia	VP_19224
Entrez Gene	19224
UniProt	P22437
Ptgs1 identified in sEVs derived from the following tissue/cell type
Basophilic leukemia cells	20424270

Gene ontology annotations for Ptgs1

Molecular Function     peroxidase activity GO:0004601 IEA     prostaglandin-endoperoxide synthase activity GO:0004666 IBA     prostaglandin-endoperoxide synthase activity GO:0004666 IEA     prostaglandin-endoperoxide synthase activity GO:0004666 ISO     oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 IBA     heme binding GO:0020037 IEA     metal ion binding GO:0046872 IEA     dioxygenase activity GO:0051213 IEA Biological Process     prostaglandin biosynthetic process GO:0001516 IMP     prostaglandin biosynthetic process GO:0001516 ISO     prostaglandin metabolic process GO:0006693 IMP     response to oxidative stress GO:0006979 IEA     learning GO:0007612 ISO     memory GO:0007613 ISO     regulation of blood pressure GO:0008217 IMP     negative regulation of norepinephrine secretion GO:0010700 ISO     cyclooxygenase pathway GO:0019371 IBA     cyclooxygenase pathway GO:0019371 IEA     cyclooxygenase pathway GO:0019371 ISO     keratinocyte differentiation GO:0030216 NAS     negative regulation of epinephrine secretion GO:0032811 ISO     maintenance of blood-brain barrier GO:0035633 ISO     regulation of cell population proliferation GO:0042127 IGI     positive regulation of vasoconstriction GO:0045907 ISO     positive regulation of smooth muscle contraction GO:0045987 ISO     cellular oxidant detoxification GO:0098869 IEA Subcellular Localization     photoreceptor outer segment GO:0001750 IDA     nucleus GO:0005634 IDA     nuclear envelope GO:0005635 ISO     cytoplasm GO:0005737 IBA     cytoplasm GO:0005737 IDA     cytoplasm GO:0005737 ISO     endoplasmic reticulum membrane GO:0005789 IEA     Golgi apparatus GO:0005794 IEA     Golgi apparatus GO:0005794 ISO     neuron projection GO:0043005 IBA     intracellular membrane-bounded organelle GO:0043231 ISO