Gene description for Gnao1
Gene name	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
Gene symbol	Gnao1
Other names/aliases	Gnao RATBPGTPC
Species	Rattus norvegicus
Database cross references - Gnao1
ExoCarta	ExoCarta_50664
Vesiclepedia	VP_50664
Entrez Gene	50664
UniProt	P59215
Gnao1 identified in sEVs derived from the following tissue/cell type
Hepatocytes	19367702

Gene ontology annotations for Gnao1

Molecular Function     GTPase activity GO:0003924 IBA     GTPase activity GO:0003924 IDA     G protein activity GO:0003925 IEA     G protein activity GO:0003925 ISO     signaling receptor binding GO:0005102 IPI     protein binding GO:0005515 IPI     GTP binding GO:0005525 IDA     GTP binding GO:0005525 IEA     GTP binding GO:0005525 ISO     GDP binding GO:0019003 TAS     G-protein beta/gamma-subunit complex binding GO:0031683 IBA     G-protein beta/gamma-subunit complex binding GO:0031683 IEA     G protein-coupled serotonin receptor binding GO:0031821 IBA     G protein-coupled serotonin receptor binding GO:0031821 IPI     mu-type opioid receptor binding GO:0031852 IBA     mu-type opioid receptor binding GO:0031852 IPI     GTPase activating protein binding GO:0032794 IPI     metal ion binding GO:0046872 IEA     corticotropin-releasing hormone receptor 1 binding GO:0051430 IBA     corticotropin-releasing hormone receptor 1 binding GO:0051430 IPI Biological Process     vesicle docking involved in exocytosis GO:0006904 IEA     vesicle docking involved in exocytosis GO:0006904 ISO     G protein-coupled receptor signaling pathway GO:0007186 IMP     G protein-coupled receptor signaling pathway GO:0007186 ISO     adenylate cyclase-modulating G protein-coupled receptor signaling pathway GO:0007188 IBA     adenylate cyclase-inhibiting serotonin receptor signaling pathway GO:0007198 IEA     adenylate cyclase-inhibiting serotonin receptor signaling pathway GO:0007198 ISO     G protein-coupled dopamine receptor signaling pathway GO:0007212 IBA     G protein-coupled dopamine receptor signaling pathway GO:0007212 IEA     G protein-coupled dopamine receptor signaling pathway GO:0007212 ISO     locomotory behavior GO:0007626 IEA     locomotory behavior GO:0007626 ISO     regulation of heart contraction GO:0008016 IEA     regulation of heart contraction GO:0008016 ISO     response to xenobiotic stimulus GO:0009410 IEP     response to organic cyclic compound GO:0014070 IEP     forebrain development GO:0030900 IEP     neuron projection development GO:0031175 IEP     response to cytokine GO:0034097 IEP     odontogenesis of dentin-containing tooth GO:0042475 IEP     response to hydrogen peroxide GO:0042542 IEP     positive regulation of GTPase activity GO:0043547 IMP     negative regulation of insulin secretion GO:0046676 IEA     negative regulation of insulin secretion GO:0046676 ISO     negative regulation of calcium ion transport GO:0051926 IMP     postsynaptic modulation of chemical synaptic transmission GO:0099170 IEA     postsynaptic modulation of chemical synaptic transmission GO:0099170 ISO     response to serotonin GO:1904014 IDA Subcellular Localization     cytoplasm GO:0005737 IBA     heterotrimeric G-protein complex GO:0005834 IBA     heterotrimeric G-protein complex GO:0005834 IEA     heterotrimeric G-protein complex GO:0005834 ISO     plasma membrane GO:0005886 ISO     dendrite GO:0030425 IEA     dendrite GO:0030425 ISO     synaptic vesicle membrane GO:0030672 IDA     presynaptic membrane GO:0042734 IEA     presynaptic membrane GO:0042734 ISO     myelin sheath GO:0043209 IDA     cell body GO:0044297 IEA     cell body GO:0044297 ISO     postsynaptic membrane GO:0045211 IEA     postsynaptic membrane GO:0045211 ISO     parallel fiber to Purkinje cell synapse GO:0098688 IDA     parallel fiber to Purkinje cell synapse GO:0098688 IEA     parallel fiber to Purkinje cell synapse GO:0098688 ISO     glutamatergic synapse GO:0098978 IEA     glutamatergic synapse GO:0098978 ISO     GABA-ergic synapse GO:0098982 IEA     GABA-ergic synapse GO:0098982 ISO