Gene description for Obsl1
Gene name obscurin-like 1
Gene symbol Obsl1
Other names/aliases AW822216
Species Mus musculus
 Database cross references - Obsl1
ExoCarta ExoCarta_98733
Vesiclepedia VP_98733
Entrez Gene 98733
UniProt D3YYU8  
 Obsl1 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Obsl1
Biological Process
    microtubule cytoskeleton organization GO:0000226 ISO
    microtubule cytoskeleton organization GO:0000226 ISS
    Golgi organization GO:0007030 ISO
    regulation of mitotic nuclear division GO:0007088 ISO
    regulation of mitotic nuclear division GO:0007088 ISS
    protein localization to Golgi apparatus GO:0034067 ISO
    positive regulation of dendrite morphogenesis GO:0050775 ISO
Subcellular Localization
    cytoplasm GO:0005737 ISO
    cytoplasm GO:0005737 ISS
    Golgi apparatus GO:0005794 IEA
    Golgi apparatus GO:0005794 ISO
    centrosome GO:0005813 ISO
    centrosome GO:0005813 ISS
    perinuclear region of cytoplasm GO:0048471 IEA
    perinuclear region of cytoplasm GO:0048471 ISO
    3M complex GO:1990393 ISO
    3M complex GO:1990393 ISS
 Experiment description of studies that identified Obsl1 in sEVs
1
Experiment ID 15
MISEV standards
✔
EM
Biophysical techniques
✔
CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Obsl1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Twist1  
Proximity Label-MS Mus musculus
View the network image/svg+xml
 Pathways in which Obsl1 is involved
No pathways found





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