Gene description for GGACT
Gene name gamma-glutamylamine cyclotransferase
Gene symbol GGACT
Other names/aliases A2LD1
Species Homo sapiens
 Database cross references - GGACT
ExoCarta ExoCarta_87769
Vesiclepedia VP_87769
Entrez Gene 87769
HGNC 25100
MIM 613378
UniProt Q9BVM4  
 GGACT identified in exosomes derived from the following tissue/cell type
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for GGACT
Molecular Function
    protein binding GO:0005515 IPI
    gamma-glutamylaminecyclotransferase activity GO:0061929 IDA
Biological Process
    modified amino acid catabolic process GO:0042219 IDA
Subcellular Localization
    cytosol GO:0005829 IBA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified GGACT in exosomes
1
Experiment ID 196
MISEV standards
EM
Biophysical techniques
Alix|TSG101|HSP70|CD9
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 197
MISEV standards
EM
Biophysical techniques
Alix|TSG101|HSP70|CD9
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for GGACT
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ORMDL1 94101
Affinity Capture-MS Homo sapiens
2 LDB2  
Two-hybrid Homo sapiens
3 RPL23A 6147
Affinity Capture-MS Homo sapiens
4 ARPC5 10092
Affinity Capture-MS Homo sapiens
5 ZBED1  
Two-hybrid Homo sapiens
6 COPS7B 64708
Affinity Capture-MS Homo sapiens
7 HRASLS5  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
8 CDX1  
Affinity Capture-MS Homo sapiens
9 CUTA 51596
Affinity Capture-MS Homo sapiens
10 COL20A1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which GGACT is involved
No pathways found





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