Gene description for FCRLA
Gene name Fc receptor-like A
Gene symbol FCRLA
Other names/aliases FCRL
FCRL1
FCRLM1
FCRLX
FCRLb
FCRLc1
FCRLc2
FCRLd
FCRLe
FCRX
FREB
Species Homo sapiens
 Database cross references - FCRLA
ExoCarta ExoCarta_84824
Vesiclepedia VP_84824
Entrez Gene 84824
HGNC 18504
MIM 606891
UniProt Q7L513  
 FCRLA identified in sEVs derived from the following tissue/cell type
Bladder cancer cells 20224111    
 Gene ontology annotations for FCRLA
Molecular Function
    transmembrane signaling receptor activity GO:0004888 IBA
Biological Process
    immune response GO:0006955 IBA
    cell surface receptor signaling pathway GO:0007166 IBA
    cell differentiation GO:0030154 IEA
Subcellular Localization
    cytoplasm GO:0005737 IDA
    external side of plasma membrane GO:0009897 IBA
 Experiment description of studies that identified FCRLA in sEVs
1
Experiment ID 76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
 Protein-protein interactions for FCRLA
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ATG16L1 55054
Affinity Capture-MS Homo sapiens
2 SNUPN 10073
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which FCRLA is involved
No pathways found





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