Gene description for Flot2
Gene name	flotillin 2
Gene symbol	Flot2
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Flot2
ExoCarta	ExoCarta_83764
Vesiclepedia	VP_83764
Entrez Gene	83764
UniProt	Q9Z2S9
Flot2 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Flot2

Molecular Function     protease binding GO:0002020 IBA     protease binding GO:0002020 IPI     protein binding GO:0005515 IPI     ionotropic glutamate receptor binding GO:0035255 IPI Biological Process     cell adhesion GO:0007155 IEA     negative regulation of gene expression GO:0010629 IEA     negative regulation of gene expression GO:0010629 ISO     regulation of heterotypic cell-cell adhesion GO:0034114 ISO     regulation of toll-like receptor 3 signaling pathway GO:0034139 ISO     positive regulation of canonical NF-kappaB signal transduction GO:0043123 IEA     positive regulation of canonical NF-kappaB signal transduction GO:0043123 ISO     protein localization to plasma membrane raft GO:0044860 IEA     protein localization to plasma membrane raft GO:0044860 ISO     regulation of myoblast differentiation GO:0045661 IBA     regulation of myoblast differentiation GO:0045661 IEA     regulation of myoblast differentiation GO:0045661 ISO     protein stabilization GO:0050821 IEA     protein stabilization GO:0050821 ISO     protein localization to plasma membrane GO:0072659 IBA     protein localization to plasma membrane GO:0072659 IEA     protein localization to plasma membrane GO:0072659 ISO     anterograde dendritic transport GO:0098937 IEA     anterograde dendritic transport GO:0098937 ISO     regulation of postsynaptic membrane neurotransmitter receptor levels GO:0099072 IEA     regulation of postsynaptic membrane neurotransmitter receptor levels GO:0099072 ISO     negative regulation of amyloid precursor protein catabolic process GO:1902992 IEA     negative regulation of amyloid precursor protein catabolic process GO:1902992 ISO     positive regulation of establishment of T cell polarity GO:1903905 IEA     positive regulation of establishment of T cell polarity GO:1903905 ISO Subcellular Localization     uropod GO:0001931 IEA     uropod GO:0001931 ISO     acrosomal membrane GO:0002080 IEA     acrosomal membrane GO:0002080 ISO     endosome GO:0005768 IEA     endosome GO:0005768 ISO     endosome GO:0005768 ISS     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 ISO     caveola GO:0005901 IDA     caveola GO:0005901 ISO     adherens junction GO:0005912 IEA     adherens junction GO:0005912 ISO     membrane GO:0016020 ISO     basolateral plasma membrane GO:0016323 IEA     basolateral plasma membrane GO:0016323 ISO     apical plasma membrane GO:0016324 ISO     flotillin complex GO:0016600 IBA     flotillin complex GO:0016600 IDA     flotillin complex GO:0016600 IEA     flotillin complex GO:0016600 ISO     lamellipodium GO:0030027 IEA     lamellipodium GO:0030027 ISO     endocytic vesicle GO:0030139 IEA     endocytic vesicle GO:0030139 ISO     endocytic vesicle GO:0030139 ISS     cortical actin cytoskeleton GO:0030864 IEA     cortical actin cytoskeleton GO:0030864 ISO     cytoplasmic vesicle GO:0031410 IBA     cytoplasmic vesicle GO:0031410 ISO     vesicle GO:0031982 ISO     dendrite cytoplasm GO:0032839 IEA     intracellular membrane-bounded organelle GO:0043231 ISO     cell-cell contact zone GO:0044291 IEA     cell-cell contact zone GO:0044291 ISO     membrane raft GO:0045121 ISO     synapse GO:0045202 EXP     synapse GO:0045202 IDA     perinuclear region of cytoplasm GO:0048471 IEA     perinuclear region of cytoplasm GO:0048471 ISO     presynaptic active zone membrane GO:0048787 EXP     presynaptic active zone membrane GO:0048787 IDA     glutamatergic synapse GO:0098978 EXP     glutamatergic synapse GO:0098978 IDA     glutamatergic synapse GO:0098978 IEA     glutamatergic synapse GO:0098978 ISO