Gene description for Bicc1
Gene name bicaudal C homolog 1 (Drosophila)
Gene symbol Bicc1
Other names/aliases Bic-C
bpk
jcpk
Species Mus musculus
 Database cross references - Bicc1
ExoCarta ExoCarta_83675
Vesiclepedia VP_83675
Entrez Gene 83675
UniProt Q99MQ1  
 Bicc1 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Bicc1
Molecular Function
    RNA binding GO:0003723 ISA
    protein binding GO:0005515 IPI
Biological Process
    kidney development GO:0001822 IMP
    determination of left/right symmetry GO:0007368 IMP
    heart development GO:0007507 IMP
    negative regulation of canonical Wnt signaling pathway GO:0090090 IEA
    negative regulation of canonical Wnt signaling pathway GO:0090090 ISO
Subcellular Localization
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified Bicc1 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Bicc1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Bicc1 is involved
No pathways found





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